Being down in the dumps is no fun, and that’s why people who have depression will stay on medications like Trintellix for as long as needed to get their depression under control. For some people that can be a very long time, and it is commonly understood that you don’t stop taking antidepressants all at once. You need to take yourself off the medication slowly with increasingly smaller doses of it. People who take the smart approach to getting off antidepressants may want to know how long does Trintellix stay in your system. 

Vortioxetine is the active ingredient in Trintellix and it’s different from other medications like Effexor in that it’s not an SSRI drug. It’s an SMS antidepressant that prevents serotonin reuptake and has the added effect of reworking the activity of serotonin receptors in the brain. Plenty of sufferers having only moderate success with treating depression see much more of it when they switch to Vortioxetine. Their doctor will inform them with what is the maximum dosage of Trintellix in the same way as they would have previously for their first antidepressant.  

It's a good example of an antidepressant for anxiety too, as the way Trintellix works to change the function of serotonin receptor activity is also helpful for making anxiety more manageable for people with GAD (generalized anxiety disorder). Depression with anxiety is not uncommon and a lot of women have this combo, and some of them who have depression and GAD will use vagus nerve breathing techniques when they’re anxious and depressed. But that has nothing to do with how long does Trintellix stay in your system.  

Less & Less 

The hope is always going to be that a person getting help with depression is going to do well with antidepressants like Trintellix. If that success does come to a point where the medication isn’t needed, then you will need to know how to wean off Trintellix. That’s not the most common verb. If you don’t know what wean means it is to gradually reduce the intake of something before eventually stopping it completely at the end of a reduction schedule. You’ll need to know how long does Trintellix stay in your system for this.  

66 hours is nearly 3 days, and that’s how long this antidepressant will stay in your system. That is based on the standard dosage, and for people who are taking Wellbutrin  it may be longer than this. So, what you may want to do to wean off this antidepressant is to progressively get closer to that hour mark before taking your next smaller dose of Trintellix. You’ll discuss with your doctor, and quite often it’s something they can detail over the phone just fine along with how long does Trintellix stay in your system.