Alprolix (Factor IX Recombinant)

Prescription medicineOnly Available By Prescription

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Alprolix (Coagulation Factor IX (Recombinant), Fc Fusion Protein) is prescribed to adults and children with hemophilia B to treat bleeding episodes, manage bleeding during surgery, and to help reduce the incidence of bleeding episodes.

Alprolix is given via a vein (intravenously).

Fact Table
Formula C2916H4484N782O836S29
License FDA approved
Bioavailability Not applicable (intravenous administration)
Legal status Prescription only
Chemical Name Coagulation factor IX (recombinant), Fc fusion protein
Elimination half-life Approximately 82 hours
Dosage (Strength) 250 IU, 500 IU, 1000 IU, 2000 IU, 3000 IU per vial
Pregnancy Consult a healthcare provider
Brands Alprolix
Protein binding Not significantly bound to plasma proteins
PubChem CID Not available
MedlinePlus a614022
ChEBI Not available
ATC code B02BD04
DrugBank DB00020
KEGG D10262
Routes of administration Intravenous

Directions

Your doctor will decide your course of treatment, including Alprolix dosing. A healthcare provider will give Alprolix via an intravenous infusion. Any questions or concerns may be referred to your doctor.

Ingredients

Coagulation Factor IX (Recombinant), Fc Fusion Protein is the active ingredient in Alprolix.

Contraindications

Alprolix should not be administered to patients who are allergic to any of Alprolix’s ingredients.

Cautions

  • Before Alprolix is initiated, tell your doctor:
    • About all the prescription and nonprescription medications you take
    • About your allergies
    • About your current health problems
    • About your past medical history
    • If you are pregnant or breastfeeding
  • Hypersensitivity reactions can occur, including the possibility of anaphylaxis.
  • Your body may produce antibodies that can affect how Alprolix works.
  • Alprolix may cause blood clotting issues.
  • Alprolix may cause kidney disorders.

Side Effects

Alprolix side effects include but are not limited to headache, abnormal sensation in the mouth, and pain in your side with blood in the urine. Contact your doctor right away if you have worrisome or persistent side effects.

Talk to your doctor about Alprolix.

References

Alprolix. Waltham, MA: Bioverativ Therapeutics Inc.; 2023.




IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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