Besponsa (Inotuzumab Ozogamicin)

Prescription medicineOnly Available By Prescription

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Besponsa (inotuzumab ozogamicin) is a medication given intravenously (IV) for the treatment of relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL) in adults.

Fact Table
Formula C6516H9996N1732O2022S40
License FDA approved
Bioavailability Not applicable (intravenous administration)
Legal status Prescription only
Chemical Name Inotuzumab Ozogamicin
Elimination half-life Approximately 12.3 days
Dosage (Strength) 0.9 mg per vial
Pregnancy Not recommended; consult a healthcare provider
Brands Besponsa
Protein binding Not extensively bound
PubChem CID 16728488
MedlinePlus a617016
ChEBI 134722
ATC code L01XC26
DrugBank DB12786
KEGG D10848
Routes of administration Intravenous

Directions

Your healthcare provider will decide on a treatment plan that’s appropriate for you. He or she will also decide on Besonspa dosing that is appropriate for you.

A healthcare professional will administer Besponsa IV infusion. If you have any questions or concerns, don’t hesitate to reach out to your healthcare provider.

Ingredients

Inotuzumab ozogamicin is the active ingredient in Besponsa.

Polysorbate 80 (0.36 mg), sodium chloride (2.16 mg), sucrose (180 mg), and tromethamine (8.64 mg) are the inactive ingredients included. Sterile Water for Injection, USP, is used for reconstitution.

Contraindications

According to the most recent Prescribing Information, there are no contraindications to Besponsa.

Cautions

  • Besponsa is associated with the following FDA Boxed Warning:
    • Liver issues, including fatal and life-threatening hepatic veno-occlusive disease (VOD), may occur
    • Patients on Besponsa had a higher post-hematopoietic stem cell transplant non-relapse mortality rate
  • Before you begin Besponsa therapy, inform your healthcare provider:
    • Of all the medications you take, including prescription and nonprescription medications, vitamins, herbals, and supplements
    • Of your allergies
    • Of your current health problems
    • Of your past medical history
    • If you are pregnant or breastfeeding
  • The following may occur during Besponsa treatment:
    • Myelosuppression, or decreased bone marrow activity
    • Infusion-related reactions
    • QT prolongation, an irregular heart rhythm
    • Harm to a fetus. Female patients should be advised to use effective contraceptive methods during treatment with Besponsa and for 8 months or longer after receiving the final dose. It is recommended that males with female partners use effective contraceptive methods during treatment and for 5 months or longer after the final dose.

Side Effects

Besponsa side effects include but are not limited to abnormal blood cell counts, infection, anemia, fatigue, bleeding, fever, nausea, headache, increased liver function tests, abdominal pain, increased gamma-glutamyltransferase, and increased bilirubin levels. Inform your healthcare provider right away of any bothersome or persistent side effects.

Talk to your healthcare provider about Besponsa.

Reference

Besponsa. Philadelphia, PA: Wyeth Pharmaceuticals LLC; 2018.




IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

product reviews icon Product Reviews