Also Known as Relvar Ellipta
Only Available By Prescription
Top brand choice
| Strength | Pack Size | Qty | |
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Strength
184/22mcg(200/25mcg) (30 doses/inhaler)
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Strength
92/22mcg(100/25mcg) (30 doses/inhaler)
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Strength
100/25mcg (14 puffs/28 blisters/inhaler)
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Strength
100/25mcg (30 puffs/60 blisters/inhaler)
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Terms & Conditions of Program
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Breo Ellipta is a prescription medication that combines two active ingredients, fluticasone furoate and vilanterol, in a dry powder inhaler. It is primarily used for the long-term maintenance and treatment of chronic obstructive pulmonary disease (COPD) and asthma.
Fluticasone furoate is an inhaled steroid that reduces inflammation in the lungs, and vilanterol is a long-acting beta-agonist (LABA) that relaxes the muscles in the airways, making breathing easier. Together, they provide anti-inflammatory and bronchodilator effects, improving lung function and reducing COPD exacerbations of asthma attacks.
| Fact Table | |
|---|---|
| Formula |
Fluticasone Furoate: C27H29F3O6S Vilanterol Trifenatate: C24H33Cl2NO10S2 |
| License | FDA approved |
| Bioavailability |
Fluticasone Furoate: Approximately 15.2% (inhalation) Vilanterol: Approximately 27% (inhalation) |
| Legal status | Prescription only |
| Chemical Name |
Fluticasone Furoate: [(6a,11ß,16a,17a)-6,9-Difluoro-17-(fluoromethylthio)-11-hydroxy-16-methyl-3-oxoandrosta-1,4-dien-17-yl 2-furoate] Vilanterol Trifenatate: [(R)-2-(4-((2-(6-((2-hydroxy-2-phenylethyl)amino)hexyl)oxy)phenyl)oxy)ethyl)-2-hydroxy-2-(4-methylsulfanylphenyl)acetate] |
| Elimination half-life |
Fluticasone Furoate: Approximately 24 hours Vilanterol: Approximately 21 hours |
| Dosage (Strength) |
100 mcg Fluticasone Furoate / 25 mcg Vilanterol per inhalation 200 mcg Fluticasone Furoate / 25 mcg Vilanterol per inhalation |
| Pregnancy | Category C; consult a healthcare provider |
| Brands | Breo Ellipta |
| Protein binding |
Fluticasone Furoate: >99% Vilanterol: >93% |
| PubChem CID |
Fluticasone Furoate: 45376022 Vilanterol: 11512638 |
| MedlinePlus | a613047 |
| ChEBI |
Fluticasone Furoate: 68563 Vilanterol: 68820 |
| ATC code | R03AK10 |
| DrugBank |
Fluticasone Furoate: DB08906 Vilanterol: DB08867 |
| KEGG |
Fluticasone Furoate: D08900 Vilanterol: D10136 |
| Routes of administration | Inhalation |
The usual dosage is one inhalation by mouth once daily. The dosage that enters the lungs will depend on the strength of the inhaler prescription.
Rinse the mouth with warm water after each inhalation. Spit out the water, and do not swallow it. Rinsing the mouth reduces the risk of oral thrush infection.
The active ingredients in Breo Ellipta are fluticasone furoate and vilanterol trifenatate.
Common drug-drug interactions with this medication may include:
Tell your doctor if you have a history of cardiovascular disease, hypertension, diabetes, or seizures before starting Breo Ellipta.
Long-term use of Breo Ellipta or use at high doses may increase the risk of pneumonia, osteoporosis, and adrenal suppression.
It is not recommended for use as a rescue medication for sudden breathing problems.
The common adverse reactions may include:
Breo Ellipta [package insert]. Durham, NC: GlaxoSmithKline; May 2023.
What is Breo Ellipta used for?
Breo Ellipta helps treat chronic obstructive pulmonary disorder (COPD) and asthma in adults. It's not for sudden breathing problems.
How to use Breo Ellipta?
Use Breo Ellipta once daily. Open it, exhale, inhale through the mouthpiece, hold your breath, then store it.
Is Breo Ellipta a steroid?
Yes, it contains fluticasone furoate, a steroid.
What is in Breo Ellipta?
Breo Ellipta has two active ingredients: fluticasone furoate and vilanterol.
How long can you stay on Breo?
It's for long-term treatment if it's safe and effective for you.
What is the best time of day to take Breo Ellipta?
Use it at the same time every day.
Does Breo improve lung function?
Yes, it improves lung function for a full day.
Does Breo help with coughing?
Yes, it can prevent and manage asthma symptoms, including coughing.
Can Breo cause weight gain?
No, Breo Ellipta does not cause weight gain.
How many puffs of Breo can you take a day?
For asthma, one puff of the 200 mcg /25 mcg dose once a day is the max.
Why is Breo so expensive?
The cost of Breo Ellipta can vary depending on insurance, pharmacy, and it's a brand-name drug with no generic version.
What happens if you suddenly stop taking Breo?
Stopping suddenly can cause withdrawal symptoms and worsen COPD or asthma. Always talk to your doctor first.
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