Bystolic (Nebivolol)

Also Known as Nebilet,Vasoxen

Prescription medicineOnly Available By Prescription
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2.5mg
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5mg
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10mg
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20mg
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Strength
2.5mg
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5mg
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10mg
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20mg
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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Bystolic (nebivolol) is a beta-adrenergic blocker medication that is used to treat high blood pressure.

Nebivolol is the Bystolic generic.


Fact Table

Formula

C22H25F2NO4

License

US DailyMed, US FDA

Bioavailability

12-96%

Legal status

Rx-Only

Chemical Name

Nebivolol

Elimination half-life

12-19 hours

Dosage (Strength)

2.5mg, 5mg, 10mg, 20mg

Pregnancy

Not recommended

Brands

Bystolic

Protein binding

98%

PubChem CID

71301

MedlinePlus

a608029

ChEBI

64022

ATC code

C07AB12

DrugBank

DB04861

KEGG

D05127

Routes of administration

By mouth

Directions

The instructions that come on your prescription's label should be followed. If you have any questions or concerns about your medication, speak with your doctor or pharmacist. 

Bystolic comes in 2.5 mg, 5 mg, 10 mg, and 20 mg oral tablets. 

The starting dose is usually 5 mg orally once a day; the medication can be taken with or without food. Every two weeks, the dose can be increased, up to 40 mg a day.

Ingredients

Nebivolol hydrochloride is contained in each Bystolic tablet. Colloidal silicon dioxide, croscarmellose sodium, D and C Red #27 Lake, FD and C Blue #2 Lake, FD and C Yellow #6 Lake, hypromellose, lactose monohydrate, magnesium stearate, microcrystalline cellulose, pregelatinized starch, polysorbate 80, and sodium lauryl sulfate are the inactive ingredients included.

Contraindications

You should not take Bystolic if you have any of the following conditions:

  • A severely low heart rate
  • Greater than first degree heart block
  • You are in cardiogenic (cardiac) shock
  • Decompensated heart failure (DHF)
  • Sick sinus syndrome (unless you have a permanent pacemaker)
  • Liver problems that are severe
  • You have an allergy to nebivolol or any of its ingredients 

Cautions

  • Before you start taking Bystolic, tell your doctor:
    • If you take any medications
    • About any allergies you may have
    • About any medical conditions you may have
    • If you are pregnant or plan to become pregnant
    • If you are breastfeeding or plan to breastfeed
  • Do not stop taking Bystolic abruptly as this can worsen coronary artery disease.
  • Symptoms of low blood sugar in diabetic patients can be masked by Bystolic. You should check your blood sugar often and treat low blood sugar as your doctor has told you.

Side Effects

The most common Bystolic side effects include headache and fatigue. 

Immediately call your doctor if you experience bothersome or persistent side effects. 

Reference:

Bystolic (nebivolol) tablets, for oral use. Madison, NJ: Allergan USA, Inc.; 2019.



IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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