Also Known as Colgout
We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!
Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.
To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.
Terms & Conditions of Program
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
COLCRYS (Colchicine) is a medication prescribed to treat gout flares and Familial Mediterranean fever (FMF). COLCRYS may also be used to prevent the recurrence of gout flares while initiating other medications that lower uric acid.
COLCRYS works by blocking the assembly of microtubules in certain cells of the immune system. Microtubules make up the internal "skeleton" of the cell. By disrupting their formation, COLCRYS prevents the activation of immune cells within the joints that normally lead to gout symptoms. COLCRYS works via a similar mechanism in FMF.
Fact Table |
|
Formula |
C22H25NO6 |
License |
FDA approved |
Bioavailability |
45% (oral) |
Legal status |
Prescription only |
Chemical Name |
Colchicine |
Elimination half-life |
26.6 - 31.2 hours |
Dosage (Strength) |
0.6 mg tablets |
Pregnancy advice |
Use only if clearly needed and the potential benefits outweigh the risks. Consult a healthcare provider. |
Brands |
Colcrys, Mitigare |
Protein binding |
39-44% |
PubChem CID |
6167 |
MedlinePlus |
a682711 |
ChEBI |
CHEBI:27882 |
ATC code |
M04AC01 |
DrugBank |
DB01394 |
KEGG |
D00570 |
Routes of administration |
Oral, Intravenous (for acute gout only) |
COLCRYS comes in COLCRYS 0.6 mg tablets. COLCRYS 0.5 mg is available in countries other than the United States, and generally, these dosages are prescribed interchangeably.
The normal dosage of COLCRYS varies based on which condition is being treated:
The active ingredient in COLCRYS is colchicine, which is also the name for COLCRYS generic.
COLCRYS has many potential drug-drug interactions. It can interact with P-GP and CYP3A4 inhibitors. Tell your doctor or pharmacist your whole list of medications before beginning COLCRYS to ensure there are no harmful drug-drug interactions.
Use COLCRYS with caution in patients with a history of kidney impairment or kidney failure. The dose may need to be adjusted.
COLCRYS should not be used by women who are pregnant or breastfeeding.
The most common adverse reactions that occur when taking COLCRYS include: