Only Available By Prescription
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Strength
200mg/25mg/300mg
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We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!
Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.
To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.
Terms & Conditions of Program
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Complera is a three-drug combination containing two nucleoside analog HIV-1 reverse transcriptase inhibitors, emtricitabine and tenofovir disoproxil fumarate, and one non-nucleoside reverse transcriptase inhibitor, rilpivirine. This three-in-one medication is used to treat HIV-1 infection in patients who weigh at least 35 kg.
Complera may not be right for everyone. Talk to your doctor about which treatment option may be best for you.
Complera comes in an oral tablet containing 200 mg of emtricitabine, 25 mg of rilpivirine, and 300 mg of tenofovir disoproxil fumarate.
The instructions that come with your Complera prescription should be carefully read and followed. Take Complera as prescribed by your doctor. Talk to your doctor or pharmacist about any questions or concerns you may have about the medication.
Adult and pediatric patients who weigh 35 kg or more are recommended to take one tablet by mouth once daily with food.
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Fact Table |
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Formula |
Emtricitabine: C8H10FN3O3S Rilpivirine: C22H18N6O Tenofovir Disoproxil Fumarate: C19H30N5O10P |
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License |
Approved by the FDA and EMA for the treatment of HIV |
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Bioavailability |
Emtricitabine: 93% Rilpivirine: 33% (under fasting conditions) Tenofovir Disoproxil Fumarate: 25% (boosted to 39% with a high-fat meal) |
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Legal status |
Rx-Only |
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Chemical Name |
Emtricitabine / Rilpivirine / Tenofovir Disoproxil Fumarate |
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Elimination half-life |
Emtricitabine: 10 hours Rilpivirine: 45 hours Tenofovir Disoproxil Fumarate: 14-17 hours |
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Dosage (Strength) |
200mg / 25mg / 300mg |
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Pregnancy |
Consult doctor |
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Brands |
Complera |
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Protein binding |
Emtricitabine: 4% Rilpivirine: 99.7% Tenofovir Disoproxil Fumarate: 0.7% to 7.2% |
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PubChem CID |
Emtricitabine: 60877 Rilpivirine: 6451161 Tenofovir Disoproxil Fumarate: 5481350 |
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MedlinePlus |
a611036 |
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ChEBI |
Emtricitabine: 31552 Rilpivirine: 59527 Tenofovir Disoproxil Fumarate: 63625 |
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ATC code |
J05AR08 |
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DrugBank |
Emtricitabine: DB00879 Rilpivirine: DB08864 Tenofovir Disoproxil Fumarate: DB00300 |
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KEGG |
Emtricitabine: D01199 Rilpivirine: D09727 Tenofovir Disoproxil Fumarate: D01982 |
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Routes of administration |
Oral |
Each Complera tablet contains two nucleoside analog HIV-1 reverse transcriptase inhibitors, emtricitabine and tenofovir disoproxil fumarate, and one non-nucleoside reverse transcriptase inhibitor, rilpivirine.
Do not take Complera with medications that can decrease its response to HIV-1 or cause medication resistance. These medications include carbamazepine, phenobarbital, phenytoin, rifampin, rifapentine, dexamethasone, St. John's wort, dexlansoprazole, esomeprazole, lansoprazole, omeprazole, pantoprazole, and rabeprazole. Ask your doctor if you do not know whether or not you take any of these medications.
Complera contains a FDA Boxed Warning regarding severe worsening of hepatitis B virus (HBV) in patients with HIV-1 and HBV who stopped taking medications containing emtricitabine and/or tenofovir disoproxil fumarate.
Common Complera side effects include depression, headache, trouble sleeping, abnormal dreams, dizziness, nausea, and rash. However, these are not all the side effects that may occur.
Contact your doctor right away if you have side effects that are bothersome or persistent.
Exceptional Customer Service
We pride ourselves on delivering excellent customer service with as much accessibility as possible.
If you have any questions at all, or would like to place an order, you are encouraged to contact us by toll-free
phone 1-888-904-8467 or email info@canadadrugsdirect.com.
Top Safety and Quality
Canada Drugs Direct employs dedicated, professional licensed pharmacists to ensure that each and every order is reviewed before it is dispensed for the safety and health of our customers. At CanadaDrugsDirect.com, your health is our top priority.
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