Cuvposa (Glycopyrrolate)

Prescription medicineOnly Available By Prescription
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Strength
1mg/5ml Oral Solution 473ml
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1mg/5ml Oral Solution 473ml
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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Cuvposa is a prescription medication used to reduce chronic severe drooling in children aged 3 to 16 years with certain neurologic conditions, such as cerebral palsy. Excessive drooling can lead to social discomfort and skin irritation, among other complications.

Glycopyrrolate, the active ingredient in Cuvposa, is an anticholinergic agent. It works by blocking acetylcholine receptors, which reduces saliva production, helping to manage and decrease drooling.

Fact Table

Formula

C19H28BrNO3

License

US FDA

Bioavailability

3% (oral)

Legal status

Prescription only

Chemical Name

(RS)-3-[2-Cyclopentyl-2-hydroxy-2-phenylacetoxy]-1,1-dimethylpyrrolidinium bromide

Elimination half-life

0.83-1.25 hours

Dosage (Strength)

1 mg/5 mL oral solution

Pregnancy

Consult a doctor

Brands

Cuvposa, Robinul, Seebri Neohaler

Protein binding

Not significantly protein bound

PubChem CID

3496

MedlinePlus

a682620

ChEBI

CHEBI:5550

ATC code

A03AB02, R03BB06

DrugBank

DB00986

KEGG

D00533

Routes of administration

Oral, Inhalation, Intravenous

Directions

Cuvposa is typically taken three times daily, 1 hour before or 2 hours after meals.

The dosage is based on the child's weight and response to treatment.

Shake the bottle well before each use.

Ingredients

The active ingredient in Cuvposa is glycopyrrolate.

Interactions

Common drug-drug interactions with this drug can include:

  • Aclidinium
  • Amantadine
  • Amifampridine
  • Amitriptyline
  • Amoxapine
  • Atropine
  • Belladonna
  • Benzhydrocodone
  • Benztropine
  • Biperiden
  • Brompheniramine
  • Buprenorphine
  • Bupropion
  • Carbinoxamine
  • Carisoprodol
  • Chlorpheniramine
  • Chlorpromazine
  • Clemastine
  • Clidinium
  • Clomipramine
  • Clozapine
  • Codeine
  • Cyclobenzaprine
  • Cyclopentolate
  • Cyproheptadine
  • Darifenacin
  • Desipramine
  • Dicyclomine
  • Dihydrocodeine
  • Dimenhydrinate
  • Diphenhydramine
  • Donepezil
  • Doxepin
  • Fentanyl
  • Fesoterodine
  • Flavoxate
  • Fluphenazine
  • Glucagon
  • Glycopyrronium Tosylate
  • Homatropine
  • Hydrocodone
  • Hydromorphone
  • Hydroxyzine
  • Hyoscyamine
  • Imipramine
  • Ipratropium
  • LetibotulinumtoxinA-wlbg
  • Loxapine
  • Meclizine
  • Mepenzolate
  • Meperidine
  • Methacholine
  • Methadone
  • Morphine
  • Morphine Sulfate Liposome
  • Nortriptyline
  • Olanzapine
  • Oliceridine
  • Orphenadrine
  • Oxitropium Bromide
  • Oxybutynin
  • Oxycodone
  • Oxymorphone
  • Paroxetine
  • Perphenazine
  • Pimozide
  • Pipenzolate Bromide
  • Pirenzepine
  • Potassium Chloride
  • Prochlorperazine
  • Procyclidine
  • Promethazine
  • Propantheline
  • Propiverine
  • Protriptyline
  • Quetiapine
  • Revefenacin
  • Scopolamine
  • Secretin Human
  • Sofpironium
  • Solifenacin
  • Stramonium
  • Sufentanil
  • Tapentadol
  • Terodiline
  • Thioridazine
  • Thiothixene
  • Tiotropium
  • Tizanidine
  • Tolterodine
  • Tramadol
  • Trifluoperazine
  • Trihexyphenidyl
  • Trimipramine
  • Tropicamide
  • Trospium
  • Umeclidinium

Cautions

Do not use Cuvposa if your child is allergic to glycopyrrolate or any other ingredients in the solution.

Inform your doctor if your child has a history of urinary retention, glaucoma, gastrointestinal disorders, or heart disease before starting this medication.

Side Effects

Common side effects may include:

  • Angle-closure glaucoma
  • Angioedema
  • Atrial fibrillation
  • Bradyarrhythmia
  • Cardiac arrest
  • Cardiac dysrhythmia
  • Constipation
  • Dyspnea
  • Flushing
  • Heat exhaustion
  • Hypersensitivity reaction
  • Malignant hyperthermia
  • Nasal congestion
  • Nasopharyngitis
  • Nystagmus
  • Paradoxical bronchospasm
  • Pseudo-obstruction of intestine
  • Respiratory arrest
  • Seizure
  • Somnolence
  • Tachycardia
  • Upper respiratory infection
  • Urinary tract infectious disease
  • Ventricular fibrillation
  • Vomiting
  • Xerostomia

References

Cuvposa [package insert]. Raleigh, NC: Merz; 2016.



IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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