Daliresp (Roflumilast)

Also Known as Daxas

Prescription medicineOnly Available By Prescription

Top brand choice

Strength Pack Size Qty
Strength
250mcg
Pack Size
Qty
Strength
500mcg
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Qty

Top Generic choice

Strength Pack Size Qty
Strength
500mcg
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Qty
What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Daliresp (Roflumilast) is a medication used to help adults with severe chronic obstructive pulmonary disease (COPD). Roflumilast helps by blocking a specific enzyme in the body that can cause lung inflammation. Daliresp may help reduce the number of times people experience worsening symptoms or flare-ups of COPD. It comes in tablet form and is usually part of a broader treatment plan to help manage the condition.

Directions

Daliresp is usually taken once a day with or without food. It's important to follow the instructions on your prescription label and not change how much you take unless your healthcare provider tells you to. The standard dose of Daliresp is 500 micrograms (mcg). Some people may start with a lower dose of 250 mcg for the first four weeks before moving up to the full dose. Doing so may help reduce the chances of stopping the medication because of side effects.

Ingredients

The active ingredient in Daliresp is Roflumilast.

Contraindications

Individuals with a known allergy to Roflumilast or any component of Daliresp should not take this medication. In addition, those with moderate-to-severe liver problems, classified as Child-Pugh class B or C, should avoid Daliresp due to an increased risk of adverse effects.

Cautions

  • Before starting treatment with Daliresp, be sure to inform your healthcare provider if you have:
    • Any existing health conditions
    • Any allergies
    • A list of all medications you are currently taking
    • Whether you are pregnant or breastfeeding
  • Daliresp is not a bronchodilator and should not be used to relieve sudden breathing difficulties or acute bronchospasm episodes.
  • Daliresp may increase the risk of psychiatric side effects such as insomnia, anxiety, depression, and suicidal thoughts or behaviors. Patients and caregivers should monitor for changes in mood or behavior and seek medical attention if symptoms worsen.
  • Use caution when prescribing Daliresp to patients with a history of depression or suicidal thoughts. Regularly evaluate the risks and benefits of continued treatment if psychiatric symptoms arise.
  • Daliresp is associated with weight loss. Monitor weight regularly during treatment. If unexplained or significant weight loss occurs, seek help from a doctor and consider discontinuing Daliresp.
  • Avoid using Daliresp with strong cytochrome P450 enzyme inducers, such as Rifampicin, Phenobarbital, Carbamazepine, or Phenytoin, as these may reduce its effectiveness.

Side Effects

The most common Daliresp side effects include diarrhea, weight loss, nausea, headache, back pain, flu-like symptoms, insomnia, dizziness, and decreased appetite. These side effects are usually mild but may persist for some individuals. If any of these symptoms bother you or do not go away, talk to your healthcare provider for guidance.

Daliresp can cause serious side effects, as highlighted in the medication's important safety information. Serious adverse reactions that occurred more frequently in patients treated with Daliresp include diarrhea, atrial fibrillation, lung cancer, prostate cancer, acute pancreatitis, and acute renal failure. If you experience any unexpected or severe symptoms, contact your healthcare provider immediately.

References

  1. Daliresp (Roflumilast) Product Monograph. Wilmington, DE: AstraZeneca Pharmaceuticals LP; 2018.
  2. Daliresp (Roflumilast) Drug Label Information. Wilmington, DE: AstraZeneca Pharmaceuticals LP; 2020.


IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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