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Strength
250mg
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500mg
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Strength
250mg powder for suspension
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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Diacomit (stiripentol) is a medication prescribed for the treatment of seizures associated with Dravet syndrome in patients who are:
Diacomit 250 mg and 500 mg suspension and capsules are available for oral administration.
Fact Table | |
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Formula | C14H18O3 |
License | FDA and EMA approved |
Bioavailability | Not well defined, varies widely |
Legal status | Prescription only |
Chemical Name | (4R)-4-(3,4-methylenedioxyphenyl)-1,2,5,6-tetrahydro-2-propylpyridine-3-carboxylic acid |
Elimination half-life | Approximately 4.5 to 13 hours |
Dosage (Strength) | 250 mg and 500 mg capsules or powder for oral suspension |
Pregnancy | Consult a healthcare provider; use only if clearly needed |
Brands | Diacomit |
Protein binding | Approximately 99% |
PubChem CID | 5025 |
MedlinePlus | a619037 |
ChEBI | 31729 |
ATC code | N03AX17 |
DrugBank | DB09048 |
KEGG | D07040 |
Routes of administration | Oral |
Diacomit should be taken as directed by the prescribing doctor, who will determine a Diacomit dosage that’s appropriate for you or your child.
Avoid breaking or opening the capsules; they should be swallowed whole with a full glass of water; take them during a meal.
Mix the powder for oral suspension in a glass of water then take immediately with a meal.
Diacomit capsules and oral suspension should be kept dry at temperatures between 20oC and 25oC (68oF and 77oF). Protect from light. Keep away from children.
Read the medication guide that comes with the prescription for further information on how to use Diacomit.
Tell your or your child’s doctor or pharmacist about any questions or concerns that arise.
Stiripentol is the active ingredient in Diacomit.
Erythrosine (250 mg capsule only), gelatin, indigotine (250 mg capsule only), magnesium stearate, povidone, sodium starch glycolate, and titanium dioxide are the inactive ingredients in the capsules.
Aspartame, carmellose sodium, erythrosine, glucose, hydroxyethylcellulose, povidone, sodium starch glycolate, sorbitol, titanium dioxide, and fruit flavor (acacia, Bergamot oil, hypromellose, maltodextrin, sorbitol, and vanillin) are the inactive ingredients in the oral suspension.
Diacomit does not have any contraindications per the most recent Prescribing Information.
Diacomit side effects include but are not limited to excessive sleepiness or drowsiness, loss of weight, loss of appetite, agitation, impaired coordination, muscle tone reduction, nausea, tremor, slurred speech, and sleep disorder.
Call a doctor right away if you or your child has side effects that become bothersome or persistent.
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Diacomit. Beauvais, France: Biocodex; 2022.