Doryx (Doxycycline Hyclate)

Prescription medicineOnly Available By Prescription
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50mg
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100mg
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Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

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What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Doryx is an antibacterial medication that your healthcare provider may prescribe to treat a variety of conditions that are caused by bacterial infection

Doryx is most commonly prescribed to treat long-term acne. Acne is a skin condition where red, bumpy, sometimes painful spots appear on the skin of the face. Acne is most common in teenagers but may be present in adults as well. It can be long-term or resolve quickly on its own.

It is unclear how Doryx helps to treat acne, but it is thought that bacteria are one of the causes of moderate to severe acne.

Fact Table

Formula

C22H24N2O8 · HCl

License

US FDA

Bioavailability

100% (oral)

Legal status

Prescription only (Rx)

Chemical Name

(4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-6-naphthacene carboxamide

Elimination half-life

16-22 hours

Dosage (Strength)

50 mg, 75 mg, 100 mg, 150 mg (delayed-release tablets)

Pregnancy

Category D (Evidence of risk)

Brands

Doryx, Doxy-100, Acticlate, Vibramycin

Protein binding

80-95%

PubChem CID

54671203

MedlinePlus

a682063

ChEBI

CHEBI:50845

ATC code

J01AA02

DrugBank

DB00254

KEGG

D07870

Routes of administration

Oral

Directions

The usual dosage of Doryx is 100 mg twice daily on the first day, and then 100 mg by mouth once daily.

The doctor may increase the dose to 100 mg twice daily if the acne is severe.

Take Doryx with a full glass of water.

Take Doryx 1 hour before or 2 hours after a meal. Avoid taking it with multivitamins that contain minerals or foods that are high in calcium.

Ingredients

The active ingredient in Doryx is doxycycline hyclate delayed-release.

Interactions

Tell your doctor and pharmacist about all medications you are taking before starting Doryx, especially:

  • Aminolevulinic Acid
  • Antacids
  • Barbiturates
  • BCG
  • Bile Acid Sequestrants
  • Bismuth Subsalicylate
  • Calcium Salts
  • Carbamazepine
  • Cholera Vaccine
  • Fosphenytoin
  • Iron Preparations
  • Lithium
  • Mecamylamine
  • Methoxyflurane
  • Multivitamins
  • Penicillin
  • Proton Pump Inhibitors
  • Quinapril
  • Sucralfate
  • Typhoid Vaccine
  • Warfarin

Cautions

Wear sun protection while using Doryx because it can increase your sensitivity to the sun.

Side Effects

Doryx side effects can include:

  • Abdominal distention
  • Abdominal pain
  • Anorexia
  • Bone growth suppression
  • Diarrhea
  • Drug reaction with eosinophilia and systemic symptoms (DRESS)
  • Erythematous rash
  • Erythema multiforme
  • Esophageal injury
  • Increased blood urea nitrogen
  • Increased lactate dehydrogenase
  • Increased serum glucose
  • Photosensitivity
  • Stevens-Johnson syndrome
  • Upper abdominal pain
  • Vulvovaginal candidiasis
  • Xerostomia

References

Doryx [package insert]. Rockaway, NJ: Warner Chilcott; 2013.


Frequently Asked Questions about Doryx (Doxycycline Hyclate)


What is Doryx (Doxycycline Hyclate)?

Doryx is a brand name for the antibiotic Doxycycline Hyclate. It belongs to the tetracycline class of antibiotics and is used to treat a variety of bacterial infections.


What conditions does Doryx treat?

Doryx is commonly used to treat infections such as acne, respiratory tract infections, urinary tract infections, and certain types of sexually transmitted infections (STIs). It may also be used for malaria prophylaxis.


How does Doryx work?

Doryx works by inhibiting the production of proteins that bacteria need to grow and multiply. This action helps to stop the spread of the infection.


Is Doryx available over the counter?

No, Doryx is not available over the counter. It requires a prescription from a healthcare provider.


What should I tell my doctor before taking Doryx?

Before taking Doryx, inform your doctor if you have any allergies, kidney or liver disease, or if you are pregnant or breastfeeding. Additionally, let your doctor know about all medications, supplements, or herbal products you are currently taking to avoid potential interactions.


How should I take Doryx?

Doryx should be taken exactly as prescribed by your doctor. It is usually taken with a full glass of water to prevent irritation of the esophagus. Avoid lying down immediately after taking Doryx.


What should I do if I miss a dose of Doryx?

If you miss a dose of Doryx, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular schedule. Do not take two doses at once to make up for a missed dose.


Are there any side effects associated with Doryx?

Common side effects of Doryx may include nausea, vomiting, diarrhea, and sensitivity to sunlight. If you experience any severe side effects or allergic reactions, seek medical attention immediately.


How long should I take Doryx?

The duration of Doryx treatment depends on the type of infection being treated. Follow your doctor's instructions carefully, and do not stop taking the medication prematurely, even if you feel better.


Is Doryx effective against viral infections like the common cold or flu?

No, Doryx is an antibiotic and is only effective against bacterial infections. It will not work against viral infections like the common cold or flu.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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