Emflaza (Deflazacort)

Prescription medicineOnly Available By Prescription
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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

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  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Emflaza is a prescription medication given to treat Duchenne muscular dystrophy in patients who are 2 years of age and older.

Deflazacort is the generic Emflaza.

Emflaza comes in tablets of 6 mg, 18 mg, 30 mg, or 36 mg for oral administration. A 22.75 mg/mL oral suspension is also available.

Fact Table
Formula C25H31NO6
License FDA approved
Bioavailability 40-60%
Legal status Prescription only
Chemical Name 11ß,21-dihydroxy-2'-methyl-5'H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione 21-acetate
Elimination half-life Approximately 1.1-1.9 hours
Dosage (Strength) 6 mg, 18 mg, 30 mg, 36 mg tablets; oral suspension 22.75 mg/mL
Pregnancy Consult a healthcare provider
Brands Emflaza
Protein binding 40%
PubChem CID 446086
MedlinePlus a617050
ChEBI 31454
ATC code H02AB13
DrugBank DB01234
KEGG D07863
Routes of administration Oral

Directions

Emflaza should be taken as your doctor has instructed. Read the medication guide that comes with your prescription if you would like additional instructions for use.

Your doctor will determine an appropriate dose for you depending on how much you weigh. It is taken once daily. If you have been taking Emflaza for more than a few days, your doctor will gradually decrease your dose.

Store Emflaza out of reach of children and at temperatures between 20°C and 25°C (68°F and 77°F).

Any questions or concerns about Emflaza may be referred to your doctor or pharmacist.

Ingredients

Deflazacort, a corticosteroid, is the active ingredient in Emflaza.

Colloidal silicon dioxide, lactose monohydrate, magnesium stearate, and pregelatinized corn starch are the inactive ingredients included in the tablet.

Acetic acid, aluminum magnesium silicate, benzyl alcohol, carboxymethylcellulose sodium, polysorbate 80, purified water, and sorbitol are the inactive ingredients included in the oral suspension.

Contraindications

Emflaza should not be given to patients who are allergic to any of its ingredients.

Cautions

  • Before Emflaza is initiated, the following should be discussed with your doctor:
    • All the prescription medications you take, including prescription and nonprescription medications, vitamins, and supplements
    • Your allergies
    • Any existing health concerns
    • Your past medical history
    • If you are pregnant or breastfeeding
  • Emflaza contains the following warnings and precautions:
    • Endocrine function changes, such as high blood sugar levels, Cushing’s syndrome, and suppression of the hypothalamic-pituitary-adrenal axis
    • Increased infection risk and weakened immune system
    • Cardiovascular and kidney function changes, including high blood pressure, increased blood sodium levels, and decreased blood potassium levels
    • Stomach/intestinal perforation
    • Behavioral or mood changes, including euphoria, sleeping problems, mood swings, severe depression, psychosis, and changes in personality
    • Bone mineral density reduction
    • Problems with the eyes such as cataracts, glaucoma, and infections
    • Live vaccines should not be administered to patients on Emflaza. Any live vaccines should be administered at least 4-6 weeks before Emflaza therapy is initiated
    • Severe skin rashes

Side Effects

Side effects of Emflaza include but are not limited to Cushingoid appearance, weight gain, increased appetite, cough, upper respiratory tract infection, daytime urinary frequency, excessive hair growth, abdominal obesity, and common cold. Contact your doctor right away if you experience bothersome or persistent side effects.

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Reference

Emflaza. South Plainfield, NJ: PTC Therapeutics, Inc.; 2021.




IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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