Emtriva (Emtricitabine)

Prescription medicineOnly Available By Prescription

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Strength Pack Size Qty
Strength
200mg
Pack Size
Qty
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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Emtriva (emtricitabine) is an oral medication prescribed with other therapies for the treatment of HIV-1 infection.

Emtriva comes in 200 mg capsules and a 10 mg/mL oral solution.

Fact Table

Formula

C8H10FN3O3S

License

US FDA

Bioavailability

~93% (oral)

Legal status

Prescription only (Rx)

Chemical Name

Emtricitabine

Elimination half-life

~10 hours (plasma); ~39 hours (intracellular)

Dosage (Strength)

200 mg capsule once daily (adults)

Pregnancy

Generally considered safe (Category B)

Brands

Emtriva; also in combination products (e.g., Truvada, Descovy)

Protein binding

<4%

PubChem CID

60877

MedlinePlus

a604004

ChEBI

47785

ATC code

J05AF09

DrugBank

DB00879

KEGG

D02654

Routes of administration

Oral

Directions

Emtriva should be taken exactly as your doctor has instructed. The medication guide that accompanies your prescription should be read carefully.

Your doctor will tell you how much medication you should take based on how old you are, how much you weigh, and your kidney function.

Speak with your doctor or pharmacist about any questions or concerns you may have.

Storage:

Store Emtriva capsules in the original container at 25°C (77°F.) Keep Emtriva away from children.

Store Emtriva oral solution in the refrigerator between 2°C and 8°C (36°F and 46°F). If Emtriva oral solution is stored at 25°C (77°F), use the medication within 3 months.

Ingredients

Emtricitabine is the active ingredient contained in Emtriva.

The inactive ingredients in Emtriva 200 mg capsules include the following: crospovidone, magnesium stearate, microcrystalline cellulose, povidone, titanium dioxide, gelatin, and FD&C blue No. 2.

Inactive ingredients in the oral solution include the following: cotton candy flavor, FD&C yellow No. 6, edetate disodium, methylparaben and propylparaben (preservatives), sodium phosphate (monobasic), propylene glycol, water, and xylitol (sweetener). To balance pH, sodium hydroxide and hydrochloric acid may be added.

Contraindications

Do not take Emtriva if you have an allergy to any of its ingredients.

Cautions

Emtriva is associated with the following FDA Boxed Warning:

  • Hepatitis B virus (HBV) that gets severely worse can occur in patients with both HIV-1 and HBV who have stopped Emtriva therapy. These patients should receive close monitoring of their liver function. HBV treatment may be necessary.
  • Before you start taking Emtriva, tell your doctor:
    • About all prescription and nonprescription medications you take
    • If you have any allergies
    • About your medical history
    • About your current health conditions
    • If you are pregnant or breastfeeding
  • Immune system problems, lactic acidosis, and liver enlargement with fat buildup in the liver may occur with Emtriva.

Side Effects

Some, but not all, side effects associated with Emtriva include headache, diarrhea, nausea, fatigue, dizziness, depression, trouble sleeping, abnormal dreams, rash, abdominal pain, weakness, increased cough, stuffy nose, and skin hyperpigmentation. If you develop bothersome or persistent side effects, immediately notify your doctor.

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Reference

Emtriva. Foster City, CA: Gilead Sciences, Inc.; 2018.




IMPORTANT NOTE: The information provided above is for general awareness and educational purposes only. It is not intended to diagnose, treat, or replace professional medical or veterinary advice. Always consult your physician, pharmacist, or veterinarian regarding the safety, suitability, and proper use of any medication for yourself or your pet.

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