Only Available By Prescription
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| Strength | Pack Size | Qty | |
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Strength
3.2mg/11.2mg
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Terms & Conditions of Program
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Evorel Conti is a hormone replacement therapy (HRT) patch used to manage symptoms of menopause in women who have not had a hysterectomy. It combines estradiol and norethisterone acetate to help alleviate menopause-related symptoms such as hot flashes, night sweats, and vaginal dryness.
Estradiol is an estrogen, while norethisterone acetate is a progestogen. Together, they work to balance hormone levels and protect the uterine lining from excessive growth, which can occur with estrogen-only treatments.
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Fact Table |
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Formula |
C18H24O2 (Estradiol) + C22H28O3 (Norethisterone acetate) |
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License |
EMA |
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Bioavailability |
30-50% (Estradiol, transdermal) + 64% (Norethisterone acetate, transdermal) |
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Legal status |
Prescription only |
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Chemical Name |
Estradiol: Estra-1,3,5(10)-triene-3,17ß-diol |
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Elimination half-life |
Approximately 4 hours (Estradiol) + 6-12 hours (Norethisterone acetate) |
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Dosage (Strength) |
Estradiol 50 mcg/24 hours + Norethisterone acetate 170 mcg/24 hours transdermal patch |
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Pregnancy |
Contraindicated |
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Brands |
Evorel Conti |
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Protein binding |
98% (Estradiol) + 61% (Norethisterone acetate) |
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PubChem CID |
5757 (Estradiol) + 6236 (Norethisterone acetate) |
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MedlinePlus |
a605042 |
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ChEBI |
CHEBI:23965 (Estradiol) + CHEBI:7627 (Norethisterone acetate) |
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ATC code |
G03FA01 |
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DrugBank |
DB00783 (Estradiol) + DB00717 (Norethisterone acetate) |
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KEGG |
D00107 (Estradiol) + D00957 (Norethisterone acetate) |
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Routes of administration |
Transdermal |
Apply one patch to a clean, dry skin area on the abdomen, buttocks, or thigh. Do not apply to the breasts.
The active ingredients in Evorel Conti are estradiol and norethisterone.
Common drug-drug interactions may include:
Tell your doctor if you have a history of blood clots, heart problems, liver disease, or cancer.
Evorel Conti is not suitable for women who are pregnant or breastfeeding. If you suspect pregnancy or become pregnant while using this medication, stop use immediately and consult your healthcare provider.
Side effects of this drug are:
Evorel Conti [package leaflet]. Monheim am Rhein, Germany: Aesica Pharmaceuticals; year.
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