Only Available By Prescription
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| Strength | Pack Size | Qty | |
|---|---|---|---|
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Strength
0.05mg
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Strength
0.1mg
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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Femring is a vaginal ring that contains a female hormone called estradiol acetate. Femring is used to treat hot flashes, vaginal irritation, and vaginal dryness in menopausal women.
| Fact Table | |
| Formula |
C18H24O2 |
| License |
EU EMA |
| Bioavailability |
Less than 5% |
| Legal status |
Rx-Only |
| Chemical Name |
Estradiol |
| Elimination half-life |
13 - 36.5 hours |
| Dosage (Strength) |
0.05mg, 0.1mg |
| Pregnancy |
Consult Doctor |
| Brands |
Femring |
| Protein binding |
98% |
| PubChem CID |
5757 |
| MedlinePlus |
a605041 |
| ChEBI |
16469 |
| ATC code |
G03CA03 |
| DrugBank |
DB00783 |
| KEGG |
D00105 |
| Routes of administration |
Ring |
You or your doctor may insert Femring. Hands should be washed before and after inserting the ring. Follow the instructions that come with your prescription. Call your doctor if you need help with inserting the ring.
Femring should remain in place for 3 months. After 3 months you should remove your old ring and insert a new ring.
The active ingredient in Femring is the female hormone, estradiol acetate.
You should not use Femring if you have any of the following conditions:
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WARNING: ENDOMETRIAL CANCER, CARDIOVASCULAR DISORDERS AND PROBABLE DEMENTIA FOR ESTROGEN-ALONE THERAPY ENDOMETRIAL CANCER There is an increased risk of endometrial cancer in a woman with a uterus who uses unopposed estrogens. Adding a progestin to estrogen therapy has been shown to reduce the risk of endometrial hyperplasia, which may be a precursor to endometrial cancer. Adequate diagnostic measures, including directed or random endometrial sampling when indicated, should be undertaken to rule out malignancy in postmenopausal women with undiagnosed persistent or recurring abnormal genital bleeding. CARDIOVASCULAR DISORDERS AND PROBABLE DEMENTIA Estrogen-alone therapy should not be used for the prevention of cardiovascular disease or dementia. The Women's Health Initiative (WHI) estrogen-alone substudy reported increased risks of stroke and deep vein thrombosis (DVT) in postmenopausal women (50 to 79 years of age) during 7.1 years of treatment with daily oral conjugated estrogens (CE) [0.625 mg], relative to placebo. The Women's Health Initiative Memory Study (WHIMS) estrogen-alone ancillary study of the WHI reported increased risk of developing probable dementia in postmenopausal women 65 years of age or older during 5.2 years of treatment with daily CE (0.625 mg)-alone, relative to placebo. It is unknown whether this finding applies to younger postmenopausal women. In the absence of comparable data, these risks should be assumed to be similar for other doses of CE and other dosage forms of estrogens. Estrogens with or without progestins should be prescribed at the lowest effective doses and for the shortest duration consistent with treatment goals and risks for the individual woman. WARNING: CARDIOVASCULAR DISORDERS, BREAST CANCER AND PROBABLE DEMENTIA FOR ESTROGEN PLUS PROGESTIN THERAPY Estrogens plus progestin therapy should not be used for the prevention of cardiovascular disease or dementia. The WHI estrogen plus progestin substudy reported increased risks of DVT, pulmonary embolism, stroke, and myocardial infarction in postmenopausal women (50 to 79 years of age) during 5.6 years of treatment with daily oral CE (0.625 mg) combined with medroxyprogesterone acetate (MPA) [2.5 mg], relative to placebo. The WHI estrogen plus progestin substudy also demonstrated an increased risk of invasive breast cancer. The WHIMS estrogen plus progestin ancillary study of the WHI reported an increased risk of developing probable dementia in postmenopausal women 65 years of age or older during 4 years of treatment with daily CE (0.625 mg) combined with MPA (2.5 mg), relative to placebo. It is unknown whether this finding applies to younger postmenopausal women. In the absence of comparable data, these risks should be assumed to be similar for other doses of CE and MPA therapy and other combinations and dosage forms of estrogens and progestins. Estrogens with or without progestins should be prescribed at the lowest effective doses and for the shortest duration consistent with treatment goals and risks for the individual woman. |
Femring can cause side effects such as breast pain, headache, spotting or irregular vaginal bleeding, stomach cramps, bloating, nausea, vomiting, and hair loss. These are not all the possible side effects. Contact your doctor right away if you experience side effects that are troublesome or persistent.
Seek emergency care immediately if you experience:
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