Flagyl (Metronidazole)

Prescription medicineOnly Available By Prescription
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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Flagyl, with the active ingredient metronidazole, is an antibiotic that treats various bacterial and parasitic infections in humans and animals. It belongs to the nitroimidazole class of antibiotics and works by disrupting the DNA and protein synthesis in microorganisms, leading to their death.

Flagyl is commonly prescribed for infections such as bacterial vaginosis, trichomoniasis, amoebiasis, and certain types of anaerobic bacterial infections in the gastrointestinal tract.

Fact Table
Formula C6H9N3O3
License FDA approved
Bioavailability Approximately 80-90% (oral)
Legal status Prescription only
Chemical Name 2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethanol
Elimination half-life Approximately 8 hours
Dosage (Strength) 250 mg, 500 mg tablets; 375 mg capsules; also available in topical and intravenous forms
Pregnancy Category B; consult a healthcare provider
Brands Flagyl, MetroGel (topical), Noritate (topical)
Protein binding Less than 20%
PubChem CID 4173
MedlinePlus a689011
ChEBI 6909
ATC code J01XD01
DrugBank DB00916
KEGG D00409
Routes of administration Oral, Intravenous, Topical, Vaginal

Directions

The dosage and direction will depend on what is being treated.

Take Flagyl exactly as prescribed, and do not stop taking it before finishing the course.

Ingredients

The active ingredient in Flagyl is metronidazole.

Interactions

The most common drug-drug interactions are:

  • Acenocoumarol
  • Adagrasib
  • Alfuzosin
  • Amiodarone
  • Amisulpride
  • Amitriptyline
  • Amprenavir
  • Anagrelide
  • Apomorphine
  • Aripiprazole
  • Aripiprazole Lauroxil
  • Arsenic Trioxide
  • Asenapine
  • Astemizole
  • Atazanavir
  • Azithromycin
  • Bepridil
  • Bedaquiline
  • Buprenorphine
  • Bupropion
  • Buserelin
  • Busulfan
  • Capecitabine
  • Ceritinib
  • Chloroquine
  • Chlorpromazine
  • Cholera Vaccine, Live
  • Cimetidine
  • Ciprofloxacin
  • Cisapride
  • Citalopram
  • Clarithromycin
  • Clofazimine
  • Clomipramine
  • Clothiapine
  • Clozapine
  • Crizotinib
  • Cyclobenzaprine
  • Dabrafenib
  • Dasatinib
  • Degarelix
  • Delamanid
  • Desipramine
  • Deslorelin
  • Deutetrabenazine
  • Dexmedetomidine
  • Disopyramide
  • Disulfiram
  • Domperidone
  • Donepezil
  • Doxepin
  • Doxifluridine
  • Droperidol
  • Dronabinol
  • Dronedarone
  • Ebastine
  • Efavirenz
  • Encorafenib
  • Entrectinib
  • Eribulin
  • Erythromycin
  • Escitalopram
  • Etrasimod
  • Famotidine
  • Felbamate
  • Fexinidazole
  • Fingolimod
  • Flecainide
  • Fluconazole
  • Fluorouracil
  • Fluoxetine
  • Formoterol
  • Foscarnet
  • Fosphenytoin
  • Fostemsavir
  • Galantamine
  • Gatifloxacin
  • Gemifloxacin
  • Gepirone
  • Glasdegib
  • Gonadorelin
  • Goserelin
  • Granisetron
  • Halofantrine
  • Haloperidol
  • Histrelin
  • Hydroquinone
  • Hydroxychloroquine
  • Hydroxyzine
  • Ibutilide
  • Iloperidone
  • Imipramine
  • Inotuzumab Ozogamicin
  • Itraconazole
  • Ivabradine
  • Ivosidenib
  • Ketoconazole
  • Lapatinib
  • Lefamulin
  • Lenvatinib
  • Leuprolide
  • Levoketoconazole
  • Levofloxacin
  • Lithium
  • Lofexidine
  • Lumefantrine
  • Macimorelin
  • Mesoridazine
  • Mebendazole
  • Mefloquine
  • Methadone
  • Methotrexate
  • Methotrimeprazine
  • Mifepristone
  • Mirtazapine
  • Mizolastine
  • Mobocertinib
  • Moricizine
  • Moxifloxacin
  • Mycophenolate Mofetil
  • Mycophenolic Acid
  • Nafarelin
  • Nelfinavir
  • Nilotinib
  • Norfloxacin
  • Octreotide
  • Ofloxacin
  • Olanzapine
  • Ondansetron
  • Osilodrostat
  • Osimertinib
  • Oxaliplatin
  • Ozanimod
  • Pacritinib
  • Paliperidone
  • Panobinostat
  • Papaverine Hydrochloride
  • Paroxetine
  • Pasireotide
  • Pazopanib
  • Pentamidine
  • Perphenazine
  • Phenobarbital
  • Phenprocoumon
  • Phenytoin
  • Pimavanserin
  • Pimozide
  • Pipamperone
  • Piperaquine
  • Pitolisant
  • Ponesimod
  • Posaconazole
  • Primidone
  • Probucol
  • Procainamide
  • Prochlorperazine
  • Promethazine
  • Propafenone
  • Protriptyline
  • Quetiapine
  • Quinidine
  • Quinine
  • Quizartinib
  • Ranolazine
  • Relugolix
  • Ribociclib
  • Risperidone
  • Ritonavir
  • Saquinavir
  • Selpercatinib
  • Sertindole
  • Sertraline
  • Sevoflurane
  • Siponimod
  • Solifenacin
  • Sorafenib
  • Sparfloxacin
  • Sotalol
  • Sulpiride
  • Sultopride
  • Sunitinib
  • Tacrolimus
  • Tamoxifen
  • Tegafur
  • Telaprevir
  • Telavancin
  • Telithromycin
  • Terfenadine
  • Tetrabenazine
  • Thioridazine
  • Tolterodine
  • Toremifene
  • Trazodone
  • Triclabendazole
  • Trimipramine
  • Triptorelin
  • Vandetanib
  • Vardenafil
  • Vemurafenib
  • Venlafaxine
  • Vilanterol
  • Vinflunine
  • Voclosporin
  • Voriconazole
  • Vorinostat
  • Warfarin
  • Zotepine
  • Ziprasidone
  • Zuclopenthixol

Cautions

Flagyl should be used with caution in patients with a history of seizures, liver dysfunction, or blood disorders.

Long-term use of Flagyl or use at high doses may increase the risk of peripheral neuropathy or antibiotic resistance.

Do not drink alcohol while taking this drug.

Side Effects

Common adverse reactions to this drug include:

  • Abdominal discomfort
  • Abnormal taste in the mouth
  • Aseptic meningitis
  • Candida infection of the genital region
  • Diarrhea
  • Disorder of optic nerve
  • Dizziness
  • Encephalopathy
  • Headache
  • Hepatic failure, acute
  • Hepatotoxicity
  • Hemolytic uremic syndrome
  • Jarisch Herxheimer reaction
  • Leukopenia
  • Nausea
  • Ototoxicity
  • Peripheral neuropathy
  • Prolonged QT interval
  • Seizure
  • Stevens-Johnson syndrome
  • Toxic epidermal necrolysis
  • Vaginal discharge
  • Vaginal irritation
  • Vaginitis

References

Flagyl [package insert]. New York, NY: Pfizer; August 2013.



IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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