Genvoya (Cobicistat/Elvitegravir/Emtricitabine/Tenofovir)

Prescription medicineOnly Available By Prescription
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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Genvoya is a four-drug combination medication that's used to treat HIV-infection in adults and pediatric patients who weigh 25 kg or more:

  • And have not received any antiretroviral treatment, or
  • Are replacing the current antiretroviral treatment and meet certain criteria

The four drugs contained in Genvoya are elvitegravir, cobicistat, emtricitabine, and tenofovir alafenamide.

Genvoya may not be right for everyone. You and your doctor should discuss treatment options that may be best for you.


Fact Table

Formula

-

License

US FDA

Bioavailability

-

Legal status

Rx-Only

Chemical Name

Cobicistat/Elvitegravir/Emtricitabine/Tenofovir

Elimination half-life

70.95 hours

Dosage (Strength)

150mg/150mg/200mg/10mg

Pregnancy

Consult Doctor

Brands

Genvoya

Protein binding

-

PubChem CID

-

MedlinePlus

-

ChEBI

-

ATC code

J05AR09

DrugBank

-

KEGG

D10756

Routes of administration

By Mouth

Directions

Take Genvoya as your doctor has prescribed. If you have any questions or concerns about the medication, talk to your doctor or pharmacist.

The recommended Genvoya dosage is to take one tablet by mouth once daily with food. 

Ingredients

Each Genvoya tablet consists of 150 mg of elvitegravir (HIV-1 integrase strand transfer inhibitor), 150 mg of cobicistat (CYP3A inhibitor), 200 mg of emtricitabine (HIV-1 nucleoside analog reverse transcriptase inhibitor), and 10 mg of tenofovir alafenamide (HIV-1 nucleoside analog reverse transcriptase inhibitor).

Croscarmellose sodium, hydroxypropyl cellulose, lactose monohydrate, magnesium stearate, microcrystalline cellulose, silicon dioxide, and sodium lauryl sulfate are the inactive ingredients. FD&C Blue No. 2/indigo carmine aluminum lake, iron oxide yellow, polyethylene glycol, polyvinyl alcohol, talc, and titanium dioxide make up the tablet coating.

Contraindications

Patients should not take Genvoya with certain drugs, including those that:

  • depend highly on CYP3A for clearance from the body and are associated with serious reactions at high levels in the body
  • are strong CYP3A inducers, which can decrease Genvoya's efficacy

Ask your doctor if you do not know whether or not you take any of these medications.

Cautions

FDA Boxed Warning: Severe acute worsening of hepatitis B have occurred in patients who are coinfected with HIV-1 and HBV and have stopped taking products containing emtricitabine and/or tenofovir disoproxil fumarate and can occur upon stopping Genvoya. Liver function should be closely monitored and treatment for hepatitis B initiated if needed.

  • Before you start taking Genvoya, discuss the following with your doctor:
    • All the prescription and over-the-counter medications you take
    • Your allergies
    • Your medical history and health problems
    • Your pregnancy or breastfeeding status
  • Genvoya may cause kidney problems. Patients' kidney function should be monitored before and during treatment with Genvoya.
  • Genvoya may cause immune system problems.
  • Genvoya may cause lactic acidosis and severe liver enlargement with fat in the liver.

Side Effects

A common Genvoya side effect is nausea. However, this is not the only side effect that Genvoya can cause. 

Call your doctor immediately if you have bothersome or persistent side effects.

Reference:

  1. Genvoya (elvitegravir, cobicistat, emtricitabine, and tenofovir alafenamide) tablets, for oral use. Foster City, CA: Gilead Sciences, Inc.; 2022.


IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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