Gonal F Prefilled Pen with Needles

Also Known as Puregon

Prescription medicineOnly Available By Prescription
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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

GONAL-F is a prescription medication used in the treatment of infertility. It contains follitropin alfa, a synthetic hormone that stimulates the growth and development of ovarian follicles in women and can induce spermatogenesis in men when administered with hCG.

GONAL-F should be prescribed by a healthcare professional experienced in treating infertility. Before starting treatment, a thorough medical evaluation is necessary to rule out any underlying conditions that may affect fertility.

GONAL-F is available in a powdered form mixed with a sterile liquid before injection. It is administered subcutaneously (under the skin).


Fact Table

Formula

C437H682N122O134S13

License

US FDA

Bioavailability

66-76%

Legal status

Rx-Only

Chemical Name

Follitropin alfa

Elimination half-life

53 hours

Dosage (Strength)

300IU / 0.5ml Prefilled Pen, 450IU / 0.75ml Prefilled Pen, 900IU / 1.5ml Prefilled Pen

Pregnancy

Contraindicated

Brands

Gonal-F

Protein binding

Not available

PubChem CID

Not available

MedlinePlus

Not available

ChEBI

Not Available

ATC code

G03GA05

DrugBank

DB00066

KEGG

D04429

Routes of administration

Subcutaneously

Directions

The dosage and timing of injections will depend on individual patient factors, such as age, weight, response to treatment, and what it's being used to treat.

Ingredients

The active ingredient in GONAL-F is follitropin alfa, which is a recombinant form of follicle-stimulating hormone (FSH).

Interactions

  • There are no known significant interactions.

Cautions

Do not use GONAL-F if you are allergic to follitropin alfa, lactose, or any other ingredient in the medication.

Tell your doctor if you have a history of ovarian cysts, abnormal vaginal bleeding, thyroid or adrenal gland disorders, or pituitary gland tumors.

GONAL-F may increase the risk of multiple pregnancies, which can lead to complications for both the mother and the fetus.

There are many possible precautions with GONAL-F. Speak to your doctor or healthcare team for a full list that applies to you.

Side Effects

Common adverse reactions may include:

  • Abdominal pain
  • Acne vulgaris
  • Acute respiratory distress syndrome
  • Anaphylaxis
  • Asthma
  • Atelectasis
  • Bruising at the injection site
  • Decreased libido
  • Diarrhea
  • Enlargement of abdomen
  • Fatigue
  • Flatulence
  • Gynecomastia
  • Headache
  • Hypersensitivity reaction
  • Inflammation at the injection site
  • Injection site reaction
  • Intermenstrual bleeding
  • Nausea
  • Nonimmune anaphylaxis
  • Ovarian cyst
  • Ovarian hyperstimulation syndrome
  • Ovarian neoplasm
  • Ovarian torsion
  • Ovary enlargement
  • Pain
  • Pain at the injection site
  • Pelvic discomfort
  • Pelvic pain
  • Seborrhea
  • Swelling at the injection site
  • Thromboembolism

References

Gonal-F [package insert]. Rockland, MA: EMD Serono, Inc; 2020.


IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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