Grifulvin V (Griseofulvin)

Also Known as Grisovin

Prescription medicineOnly Available By Prescription
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Strength Pack Size Qty
Strength
500mg
Pack Size
Qty

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Your doctor may prescribe Grifulvin V to treat a group of infections called dermatophyte infections. These types of infections are fungal skin infections that can affect the hair, nails, and skin. Common symptoms may include itching, scaling, discoloration, and rashing of the area.

Grifulvin is an antifungal medication that works by stopping the replication of fungal cells. It is incorporated into keratin (a protein in the skin, hair, and nails) to prevent future infections.

Fact Table

Formula

C17H17ClO6

License

US FDA

Bioavailability

25 to 70%

Legal status

Rx-Only

Chemical Name

Griseofulvin

Elimination half-life

9–21 hours

Dosage (Strength)

500mg

Pregnancy

Consult Doctor

Brands

Gris-peg, Grifulvin V

Protein binding

84%

PubChem CID

441140

MedlinePlus

a682295

ChEBI

27779

ATC code

D01AA08

DrugBank

DB00400

KEGG

D00209

Routes of administration

By mouth

Directions

Grifulvin is available in 125 mg, 250 mg, and 500 mg tablets. The starting dosage is usually 250 mg twice daily or 500 mg once daily.

Your healthcare provider may increase your dosage to 750-1000 mg by mouth divided into one or more doses per day for severe infections.

Grifulvin can be taken with or without food.

Ingredients

The active ingredient in Grifulvin V generic is griseofulvin.

Interactions

The most common drug-drug interactions with this medication include:

  • Alcohol 
  • Aminolevulinic Acid
  • Barbiturates
  • Carbocisteine
  • Cyclosporine
  • Hormonal contraceptives
  • Saccharomyces boulardii
  • Warfarin

Cautions

Tell your doctor immediately if a rash develops when you start Grifulvin V.

Use caution if you have a history of liver problems before taking this medication because it can cause liver problems.

If you have a history of allergy to penicillin, there is a potential for cross-reaction with Grifulvin V.

It is recommended to wear sunscreen while you take this medication.

Side Effects

Tell your healthcare providers if you experience any of the following Grifulvin V side effects:

  • Angioedema
  • Confusion
  • Dermatologic reaction
  • Diarrhea
  • Dizziness
  • Epigastric distress
  • Fatigue
  • Gastrointestinal hemorrhage
  • Granulocytopenia
  • Headache
  • Hepatotoxicity
  • Increased liver enzymes
  • Increased serum bilirubin
  • Insomnia
  • Nausea
  • Nephrosis
  • Oral candidiasis
  • Paresthesia
  • Skin photosensitivity
  • Skin rash
  • Toxic epidermal necrolysis
  • Urticaria
  • Vomiting

References

  1. Grifulvin V [package insert]. Los Angeles, CA: Ortho Dermatologics; 2011.


IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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