Hulio (Adalimumab)

Description

Hulio is an injection available by prescription only. It is used for the treatment of rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, adult crohn's disease, ulcerative colitis, and plaque psoriasis.

Hulio is supplied as a 40 mg/0.8 mL single-dose prefilled pen for injection. It is also supplied as a prefilled plastic syringe for injection in the following strengths:

• 40 mg/0.8 mL
• 20 mg/0.4 mL

Directions

The instructions that come with your Hulio prescription should be carefully read and followed. Use Hulio as prescribed by your doctor. Tell your doctor or pharmacist about any questions or concerns you may have.

Hulio dosage depends on the condition being treated. It also depends on the weight of the patient when being used to treat juvenile idiopathic arthritis. 

Your healthcare provider will teach you how and when to inject Hulio. Wait until your healthcare provider has shown you how to properly inject Hulio before you inject it yourself. 

Ingredients

The active ingredient in Hulio is adalimumab-fkjp, a tumor necrosis factor (TNF) blocker.

Methionine, monosodium glutamate, polysorbate 80, sorbitol, and Water for Injection, USP are the inactive ingredients. Hydrochloric acid is also added for pH balance. 

Contraindications

Hulio has no known contraindications.

Cautions

Hulio has FDA Boxed Warnings regarding the increased risk of serious infections that can lead to hospitalization or death. In addition, there is a FDA Boxed Warning regarding the risk of lymphoma and other malignancies that can be fatal with the use of TNF blockers, including adalimumab products.

• Before beginning treatment with Hulio, discuss the following with your doctor:
• All the medications you use
• Your allergies
• Your health history and current health problems
• Your pregnancy or breastfeeding status
• Hulio has been associated with serious allergic reactions, including anaphylaxis. Seek emergency care immediately if you experience difficulty breathing, a rash, swelling of your lips, tongue, or throat, or other signs and symptoms of a severe reaction.
• Hepatitis B virus in patients who are carriers of the virus may be reactivated with Hulio use.
• Multiple sclerosis, optic neuritis, or Guillain-Barré syndrome may occur or worsen with Hulio use.
• Hulio may cause abnormal blood cell counts. Seek medical care right away if you experience signs and symptoms of blood disorders or infection, including fever, bruising, bleeding, or pale appearance of the skin.
• Hulio may cause heart failure. Seek medical care immediately if you experience difficulty breathing, swelling, or rapid weight gain.
• Hulio may cause lupus-like syndrome.
• Live vaccines are not recommended during treatment with Hulio.

Side Effects

Infections, injection site reactions, headache, and rash are some Hulio side effects. However, contact your doctor right away if you experience side effects that bother you or won't go away.

Reference:

1. Hulio (adalimumab-fkjp) injection, for subcutaneous use. Morgantown, WV: Mylan Pharmaceuticals Inc.; 2020.

About Dr. Savannah Muncy (Page Author)

Dr. Muncy (PharmD) studied science and education as an undergraduate before attending the Appalachian College of Pharmacy where she completed her PharmD in three years. She is currently using her pharmacy and healthcare expertise to write medical content for clients all around the world. She is focused on delivering the most current, accurate, and engaging information to healthcare professionals and patients. Read More....