Cortate Cream (Hydrocortisone)

Also Known as Dioderm, Cortef

Prescription medicineOnly Available By Prescription

Top Generic choice

Strength Pack Size Qty
Strength
1%
Pack Size
Qty
Strength
2.5%
Pack Size
Qty
What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Cortate Cream, commonly known as Hydrocortisone, is a corticosteroid medication used to provide temporary relief from minor skin irritations. It works by reducing inflammation, redness, and itching to help calm the skin. Classified as a topical steroid, Hydrocortisone cream may treat a variety of dermatological conditions, including eczema, dermatitis, insect bites, poison ivy, poison oak, and poison sumac. It is generally applied directly to the affected area for symptomatic relief.

Fact Table

Formula

C21H30O5

License

Health Canada, US FDA

Bioavailability

Variable (depends on route of administration)

Legal status

OTC (low-strength), Prescription (higher strengths)

Chemical Name

11ß,17,21-Trihydroxypregn-4-ene-3,20-dione

Elimination half-life

1.5–2 hours

Dosage (Strength)

0.5% (OTC), 1% (OTC/Prescription), 2.5% (Prescription)

Pregnancy

Consult a doctor (generally considered safe for topical use in low doses)

Brands

Cortate, Cortisone-10, Hydroval, Locoid

Protein binding

Cortate, Cortisone-10, Hydroval, Locoid

PubChem CID

5754

MedlinePlus

a682793

ChEBI

17650

ATC code

D07AA02

DrugBank

DB00741

KEGG

D00068

Routes of administration

Topical

Directions

When using Hydrocortisone, it's important to apply the medication to the affected area with clean hands. The standard dosage will depend on the strength of the cream. A thin layer can be gently applied to the irritated skin not more than 3 or 4 times a day, or as instructed by a healthcare provider. Typically, usage should not exceed 7 consecutive days without medical advice. After application, avoid covering the treated area with occlusive dressings unless directed by a doctor. Wash hands thoroughly after handling the medication.

Ingredients

The active ingredient in Cortate is Hydrocortisone.

Contraindications

Avoid using this medication if you have a known allergy to Hydrocortisone or any components in Cortate Cream.

Cautions

  • Before using Cortate, consult a healthcare provider about the following:
    • Any existing health conditions
    • Any allergies
    • A list of all medications you are currently taking
    • Whether you are pregnant or breastfeeding
  • Using Cortate over large areas of the body, for long periods, or under bandages can lead to hormone imbalances, potentially causing symptoms like fatigue, weight gain, or high blood sugar. If long-term or high-dose use is necessary, your doctor may check your hormone levels to monitor for these effects.
  • If the treated skin becomes irritated, Cortate should be stopped, and another treatment may be needed. If you have a skin infection, your doctor may prescribe an antifungal or antibiotic along with Cortate. If the infection does not improve, stop using Cortate until the infection is controlled.
  • Hydrocortisone should only be used as directed by your doctor and for the condition it was prescribed. Avoid applying it to the eyes, and do not use it under tight bandages unless instructed.
  • Children absorb more Cortate through the skin than adults, making them more prone to side effects like growth delays or hormone imbalances. If using Cortate in a child, avoid covering the treated area with tight diapers or plastic pants, as this can increase absorption.
  • The effects of topical Cortate on pregnancy are not well studied, but some corticosteroids have caused birth defects in animal studies. It should only be used during pregnancy if absolutely necessary. While small amounts may pass into breast milk, it is not known if this is harmful to a nursing baby.

Side Effects

The most common side effects of Cortate include burning, itching, irritation, and dryness at the application site. Some individuals may also experience folliculitis, increased hair growth (hypertrichosis), or acne-like eruptions. Skin changes such as hypopigmentation or perioral dermatitis may occur with prolonged use. These effects are usually mild and may improve after discontinuing treatment.

In rare cases, Cortate may cause skin thinning (atrophy), stretch marks (striae), or secondary infections, particularly when used with occlusive dressings. Allergic contact dermatitis can develop, leading to increased redness and discomfort. Excessive moisture retention (maceration) or miliaria (heat rash) may also occur. If you notice signs of a severe reaction, such as persistent irritation or infection, consult a healthcare provider.

References

  1. Hydrocortisone Cream Drug Label Information. Hawthorne, NY: Taro Pharmaceuticals U.S.A., Inc.; 2014.


IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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