Top brand choice
Strength | Pack Size | Qty | |
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Strength
50mg
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We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!
Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.
To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.
Terms & Conditions of Program
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Ibsrela, also known as Tenapanor, is a medicine used to treat irritable bowel syndrome with constipation (IBS-C) in adults. This condition causes discomfort in the gut and makes it hard to have regular bowel movements. The Ibsrela mechanism of action involves blocking a specific protein in the gut that normally helps absorb sodium. By doing this, it allows more water to stay in the intestines, which can lead to softer stools and more frequent bowel movements.
Fact Table | |
Formula | C50H66F3N9O10S2 |
License | US FDA |
Bioavailability | Minimal (local action in the gut) |
Legal status | Prescription only (Rx) |
Chemical Name | (2R)-2-({[(2S)-1-(2-{[2-fluoro-5-(trifluoromethyl)phenyl]sulfonyl}benzyl)pyrrolidine-2-carbonyl]amino}acetyl)amino}-3-(3-hydroxy-3-phenylpropanamido)propanoic acid |
Elimination half-life | Not systemically absorbed |
Dosage (Strength) | 50 mg tablets |
Pregnancy | Consult a doctor (No data in humans; Animal studies show some risk) |
Brands | Ibsrela |
Protein binding | Not applicable (acts locally in the gut) |
PubChem CID | 71582774 |
MedlinePlus | a620036 |
ChEBI | 134713 |
ATC code | A06AX07 |
DrugBank | DB11763 |
KEGG | D10925 |
Routes of administration | Oral |
Ibsrela is typically taken as a 50 mg tablet twice daily, ideally right before breakfast and dinner. It's important to adhere to this schedule for the medication to be most effective. If you miss a dose, do not double up; instead, continue with your regular dosing schedule.
Tenapanor is the active ingredient in Ibsrela.
Avoid taking or using Ibsrela if any of the following apply:
Ibsrela mainly causes diarrhea, which can occasionally be severe. Should you experience intense diarrhea, it’s recommended to stop using Ibsrela and consult your doctor. Besides diarrhea, other usual side effects include a feeling of abdominal swelling or pressure, gas, and dizziness.
If you encounter severe diarrhea or the other side effects become troublesome, it's important to reach out to your healthcare provider. Managing these side effects immediately helps maintain your health and well-being while on this medication.