Also Known as Jakavi
Only Available By Prescription
Top brand choice
| Strength | Pack Size | Qty | |
|---|---|---|---|
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Strength
5mg
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Strength
10mg
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Strength
15mg
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Strength
20mg
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Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.
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Terms & Conditions of Program
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Jakafi is a medication prescribed for the treatment of certain blood disorders. It belongs to a class of drugs called Janus kinase (JAK) inhibitors, which block specific enzymes involved in the growth and survival of abnormal blood cells.
Jakafi is primarily used to treat myelofibrosis (a rare type of bone marrow disorder), and polycythemia vera, a condition characterized by an overproduction of red blood cells. It helps to reduce symptoms such as enlarged spleen, fatigue, and itching and may also improve the overall quality of life for individuals affected by these conditions.
| Fact Table | |
| Formula |
C17H18N6 |
| License |
EU EMA |
| Bioavailability |
95% |
| Legal status |
Rx-Only |
| Chemical Name |
Ruxolitinib |
| Elimination half-life |
2.8-3 hours |
| Dosage (Strength) |
5mg, 15mg, 20mg |
| Pregnancy |
Consult Doctor |
| Brands |
Jakafi |
| Protein binding |
97% |
| PubChem CID |
25126798 |
| MedlinePlus |
a612006 |
| ChEBI |
66919 |
| ATC code |
L01EJ01 |
| DrugBank |
DB08877 |
| KEGG |
D09959 |
| Routes of administration |
By mouth |
Your healthcare team will determine the correct dose of Jakafi. Take it exactly as prescribed, and do not change the dosage without speaking with your physician.
Jakafi can be taken with or without food.
The active ingredient in Jakafi is Ruxolitinib.
Common drug-drug interactions may include:
Your doctor should perform routine skin examinations while you take Jakafi.
Tell your doctor if you have a history of heart problems.
Ask your doctor and pharmacist about the full list of precautions.
Common side effects may include:
Jakafi [package insert]. Wilmington, DE: Incyte Corporation; 2021.
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