Only Available By Prescription
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| Strength | Pack Size | Qty | |
|---|---|---|---|
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Strength
50mg/500mg
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Strength
50mg/850mg
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Strength
50mg/1000mg
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You'll have option to make 4 interest-free payments by credit card once your order is confirmed using
We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!
Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.
To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.
Terms & Conditions of Program
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
This medicine is a dipeptidyl peptidase-4 enzyme inhibitor and biguanide antidiabetic combination used along with a diet and exercise program to control high blood sugar in certain patients with type 2 diabetes.
| Fact Table |
|
| Formula |
Sitagliptin: C16H15F6N5O; Metformin: C4H11N5 |
| License |
FDA approved |
| Bioavailability |
Sitagliptin: ~87%; Metformin: 50-60% |
| Legal status |
Prescription medicine |
| Chemical Name |
Sitagliptin: 7-[(3R)-3-Amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine; Metformin: N,N-dimethylimidodicarbonimidic diamide |
| Elimination half-life |
Sitagliptin: ~12.4 hours; Metformin: ~6.2 hours |
| Dosage (Strength) |
Available in combinations of 50mg Sitagliptin/500mg Metformin, 50mg Sitagliptin/1000mg Metformin, and others |
| Pregnancy advice |
Use only if clearly needed and the potential benefits outweigh the risks. Consult a healthcare provider. |
| Brands |
Janumet |
| Protein binding |
Sitagliptin: 38%; Metformin: Not significant |
| PubChem CID |
Sitagliptin: 4369359; Metformin: 4091 |
| MedlinePlus |
a606023 |
| ChEBI |
Sitagliptin: CHEBI:40237; Metformin: CHEBI:6801 |
| ATC code |
A10BD07 |
| DrugBank |
Sitagliptin: DB01261; Metformin: DB00331 |
| KEGG |
Sitagliptin: D08514; Metformin: D04966 |
| Routes of administration |
Oral |
Follow the directions for using this medicine provided by your doctor. This medicine may come with a patient information leaflet. Read it carefully. Ask your doctor, nurse, or pharmacist any questions that you may have about this medicine. TAKE THIS MEDICINE with food. DRINK PLENTY OF FLUIDS while taking this medicine. STORE THIS MEDICINE at room temperature between 68 and 77 degrees F (20 and 25 degrees C), in a tightly-closed container, away from heat, moisture, and light. Brief storage between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Take this medicine regularly to receive the most benefit from it. Taking this medicine at the same times each day will help you to remember. CONTINUE TO TAKE THIS MEDICINE even if you feel well. Do not miss any doses. IF YOU MISS A DOSE OF THIS MEDICINE, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. DO NOT take 2 doses at once.
SIDE EFFECTS that may occur while taking this medicine include diarrhea, gas, headache, indigestion, nausea, sore throat, stomach pain or upset, stuffy or runny nose, vomiting, or weakness. If they continue or are bothersome, check with your doctor. CONTACT YOUR DOCTOR IMMEDIATELY if you experience chest pain or discomfort; dizziness or lightheadedness; fast or difficult breathing; fever, chills, or persistent sore throat; feeling of being unusually cold; general feeling of being unwell; muscle pain or weakness; red, blistered, swollen, or peeling skin; slow or irregular heartbeat; swelling of your hands, legs, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; unusual hoarseness; unusual or persistent stomach pain or discomfort; unusual drowsiness; or unusual tiredness or weakness. An allergic reaction to this medicine is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include rash, itching, swelling, severe dizziness, or trouble breathing. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist.
Some common side effects that you may experience with Janumet medication are:
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