Kerendia (Finerenone)

Prescription medicineOnly Available By Prescription
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Strength Pack Size Qty
Strength
10mg
Pack Size
Qty
Strength
20mg
Pack Size
Qty

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Kerendia (finerenone) is used to help slow the progression of chronic kidney disease and decrease the risk of heart attack, cardiovascular death, and heart failure hospitalization in adults who have type 2 diabetes.


Fact Table

Formula

C21H22N4O3

License

US DailyMed

Bioavailability

43.5%

Legal status

Rx-Only

Chemical Name

Finerenone

Elimination half-life

17.4 hours

Dosage (Strength)

10mg, 20mg

Pregnancy

Consult Doctor

Brands

Kerendia

Protein binding

92%

PubChem CID

60150535

MedlinePlus

a621038

ChEBI

-

ATC code

C03DA05

DrugBank

DB16165

KEGG

D10633

Routes of administration

By mouth

Directions

Kerendia comes in oral tablet strengths of 10 mg and 20 mg.

The instructions that come with your Kerendia prescription should be followed. Talk to your doctor or pharmacist about any questions or concerns you may have about the medication.

Before starting on Kerendia, your doctor will evaluate your kidney function and blood potassium levels to determine the right starting dose for you. The general starting dose is 10 mg or 20 mg by mouth one time a day with or without food. After 4 weeks of treatment, your doctor may evaluate your kidney function and blood potassium levels and decide to increase your dose to 20 mg one time a day if appropriate.

Ingredients

The active ingredient in Kerendia is finerenone, a nonsteroidal mineralocorticoid receptor antagonist.

Contraindications

Avoid taking Kerendia with other CYP3A4 inhibitors. If you are unsure whether or not you are taking other CYP3A4 inhibitors, ask your doctor.

Avoid taking Kerendia if you have a condition in which your adrenal glands do not produce enough hormones.

Cautions

  • Before you start taking Kerendia, talk to your doctor about:
    • All the medications you take, including prescription, nonprescription, vitamins, and herbal supplements
    • Your allergies
    • Your medical problems, including problems with your liver
    • The status of pregnancy or if you plan to become pregnant
    • The status of breastfeeding or if you plan to breastfeed. It is not recommended to breastfeed while taking Kerendia and for one day after discontinuing Kerendia.
  • Elevated potassium levels in the blood can occur with the use of Kerendia. Immediately get medical care if you have muscle weakness, racing heart, breathing issues, chest pain, nausea, or vomiting.
  • Grapefruit or grapefruit juice should be avoided while taking Kerendia.

Side Effects

Elevated potassium levels in the blood, low blood pressure, and low sodium levels are the most common side effects of Kerendia. However, other side effects can occur with the use of Kerendia. Immediately tell your doctor if your side effects trouble you or won't go away.

References:

  1. Kerendia (finerenone) tablets, for oral use. Whippany, NJ: Bayer HealthCare Pharmaceuticals, Inc.; 2021.
  2. Kerendia (finerenone) tablets. Important Safety Information. Accessed March 25, 2022.
  3. Adrenal Insufficiency. Endocrine Society. January 23, 2022. Accessed March 25, 2022.
  4. What is Hyperkalemia? National Kidney Foundation. Accessed March 25, 2022.


IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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