Leqembi (Lecanemab)

Prescription medicineOnly Available By Prescription

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Leqembi (Lecanemab) is a prescription drug developed for the treatment of Alzheimer's disease. As a monoclonal antibody, Leqembi targets and supports the reduction of amyloid beta plaques in the brain, which are associated with the progression of Alzheimer's. Healthcare providers may recommend it for patients showing mild cognitive impairment or mild dementia stages of Alzheimer's.

Directions

Leqembi is an injectable medication that is administered intravenously, which means directly into the bloodstream. The standard dosage for Leqembi is 10 mg/k once every two weeks. The medication must be diluted before administration, which involves withdrawing the necessary volume from the vial and adding it to an infusion bag with 0.9% Sodium Chloride Injection, USP. Patients or caregivers should be aware that each vial of Leqembi is for single use and that any unused portion should be discarded.

Ingredients

Leqembi consists of the active ingredient Lecanemab. The formula also includes several inactive ingredients that help stabilize the solution and facilitate its administration. The inactive ingredients may include arginine hydrochloride, histidine, polysorbate 80, and water for injection.

Contraindications

Individuals should avoid taking or using Leqembi if there is a known severe hypersensitivity to Lecanemab-irmb or any ingredients of the formulation. A history of allergic reactions may pose a high risk for severe complications.

Cautions

  • Before starting treatment with Leqembi, consult a healthcare provider about the following:
    • Any medical conditions.
    • All medications, including over-the-counter drugs, supplements, and herbal products.
    • Whether you’re pregnant or breastfeeding.
    • Any allergic reactions to medications.
  • Leqembi may cause amyloid related imaging abnormalities (ARIA). ARIA often has no symptoms, but can occasionally lead to serious events, including large intracerebral hemorrhages.
  • People who have two copies of the ApoE e4 gene (homozygotes) are more likely to experience ARIA, including serious cases, compared to those with one or no copies. Discuss with your doctor about testing for ApoE e4 status before beginning treatment.
  • Watching for signs of ARIA is recommended during the first 14 weeks of Leqembi treatment, especially if you are an ApoE e4 homozygous. If symptoms suggesting ARIA occur, it's important to undergo a clinical evaluation, which may include an MRI scan.
  • Infusion-related reactions can occur with Leqembi. If such reactions happen, the infusion rate might need to be reduced or stopped, with appropriate medical treatment provided. Pre-medication with antihistamines, NSAIDs, or corticosteroids may be considered for future doses.

Side Effects

Leqembi may lead to a range of side effects. Common Leqembi side effects include mild infusion-related reactions, with symptoms like nausea, vomiting, flu-like symptoms, fever, and dizziness. These are typically not severe, but they can affect daily activities.

The medication may also trigger more serious side effects, such as allergic reactions. Signs of an allergic reaction may include hives, difficulty breathing, and swelling of the face, lips, tongue, or throat. Monitor for these side effects and seek medical attention if they develop.

References:

  1. Leqembi (Lecanemab) Product Monograph. Nutley, NJ: Eisai Inc; 2023.
  2. Leqembi (Lecanemab) Drug Label Information. Nutley, NJ: Eisai Inc; 2023.



IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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