Also Known as maviret
Only Available By Prescription
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| Strength | Pack Size | Qty | |
|---|---|---|---|
|
Strength
100/40mg
|
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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Mavyret (glecaprevir and pibrentasvir) is a medication prescribed to adults and pediatric patients who are 3+ years old who have a certain chronic hepatitis C virus (HCV) genotype infection with or without compensated cirrhosis or with HCV genotype 1 infection who was previously treated with another certain therapy.
Mavyret tablets contain 100 mg glecaprevir and 40 mg pibrentasvir for oral administration. It also comes in oral pellets that contain 50 mg glecaprevir and 20 mg pibrentasvir.
| Fact Table |
|
| Formula |
C38H46N6O9S2 (Glecaprevir), C57H65F5N10O8 (Pibrentasvir) |
| License |
US FDA |
| Bioavailability |
Not well established |
| Legal status |
Prescription only (Rx) |
| Chemical Name |
Glecaprevir, Pibrentasvir |
| Elimination half-life |
6 hours (Glecaprevir), 23 hours (Pibrentasvir) |
| Dosage (Strength) |
100 mg Glecaprevir / 40 mg Pibrentasvir per tablet |
| Pregnancy |
Consult a doctor |
| Brands |
Mavyret |
| Protein binding |
97.5% (Glecaprevir), 99.9% (Pibrentasvir) |
| PubChem CID |
54767960 (Glecaprevir), 44631912 (Pibrentasvir) |
| MedlinePlus |
a617048 |
| ChEBI |
145373804 (Glecaprevir), 145365096 (Pibrentasvir) |
| ATC code |
J05AP57 |
| DrugBank |
DB13879 (Glecaprevir), DB13878 (Pibrentasvir) |
| KEGG |
D10833 (Glecaprevir), D10834 (Pibrentasvir) |
| Routes of administration |
Oral |
Patients should take Mavyret as the doctor has prescribed. The doctor will determine an appropriate dosage for the patient depending on their age and weight.
For additional usage instructions, consult the medication guide included with the Mavyret prescription.
Keep Mavyret stored at or below 30°C (86°F); keep away from children.
Refer any questions or concerns to the doctor or pharmacist.
Glecaprevir and pibrentasvir are the active ingredients in Mavyret medication.
Colloidal silicon dioxide, copovidone (type K 28), croscarmellose sodium, hypromellose 2910, iron oxide red, lactose monohydrate, polyethylene glycol 3350, propylene glycol monocaprylate (type II), sodium stearyl fumarate, titanium dioxide, and vitamin E (tocopherol) polyethylene glycol succinate are the inactive ingredients in the tablets.
Colloidal silicon dioxide, copovidone (type K 28), croscarmellose sodium, hypromellose 2910, iron oxide red, iron oxide yellow, lactose monohydrate, polyethylene glycol/macrogol 3350, propylene glycol monocaprylate (type II), sodium stearyl fumarate, titanium dioxide, and vitamin E (tocopherol) polyethylene glycol succinate are the inactive ingredients in the oral pellets.
Mavyret should not be administered to patients with moderate or severe liver dysfunction or who have had previous liver decompensation.
Mavyret should not be taken with atazanavir or rifampin.
Mavyret side effects include but are not limited to headache and fatigue.
Patients are advised to contact their doctor if they experience any bothersome or persistent side effects.
Here, you can buy Mavyret with a valid prescription!
Mavyret. North Chicago, IL: AbbVie Inc.; 2023.
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