Mayzent (Siponimod)

Prescription medicineOnly Available By Prescription
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Strength Pack Size Qty
Strength
0.25mg
Pack Size
Qty
Strength
2mg
Pack Size
Qty

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Mayzent (siponimod) is a medication that is prescribed to adults for the treatment of relapsing forms of multiple sclerosis.

Mayzent comes in 0.25 mg, 1 mg, and 2 mg tablets for oral administration.

Fact Table
Formula C29H35F3N2O3
License FDA approved
Bioavailability 84%
Legal status Prescription only
Chemical Name Siponimod
Elimination half-life Approximately 30 hours
Dosage (Strength) 0.25 mg, 2 mg tablets
Pregnancy Consult a healthcare provider
Brands Mayzent
Protein binding >99.9%
PubChem CID 57382290
MedlinePlus a619013
ChEBI 145426
ATC code L04AA42
DrugBank DB11767
KEGG D10720
Routes of administration Oral

Directions

Mayzent should be taken as your healthcare provider has directed. The medication guide that accompanies your prescription should be thoroughly read.

Mayzent dosing:

Your healthcare provider will decide on appropriate dosing for you. Avoid crushing, splitting, or chewing the tablets.

Mayzent storage:

Store Mayzent tablets at room temperature between 68°F and 77°F (20°C and 25°C) for up to 3 months maximum. Unopened Mayzent tablets may be refrigerated between 36°F and 46°F (2°C to 8°C) if you need to store them for more than 3 months. However, they should not be put back in the refrigerator once you open the containers.

Keep the medication away from children.

Any questions or concerns may be referred to your healthcare provider or pharmacist.

Ingredients

Siponimod is the active ingredient in Mayzent.

Colloidal silicon dioxide, crospovidone, glyceryl dibehenate, lactose monohydrate, microcrystalline cellulose, with a film coating containing iron oxides (black and red iron oxides for the 0.25 mg and 1 mg strengths and red and yellow iron oxides for the 2 mg strength), lecithin (soy), polyvinyl alcohol, talc, titanium dioxide, and xanthan gum are the inactive ingredients included.

Contraindications

Mayzent should not be given to patients who have any of the following conditions:

  • A CYP2C9*3/*3 genotype
  • History of heart attack, unstable angina (a type of chest pain), stroke, mini stroke, hospitalized with decompensated heart failure, or Class III/IV heart failure within in the last 6 months
  • Mobitz type II second-degree, third-degree AV block, or sick sinus syndrome, unless a functioning pacemaker is in use

Cautions

  • Before you start treatment with Mayzent, inform your healthcare provider:
    • Of all the medications you take, including prescription and nonprescription medications, vitamins, herbals, and supplements
    • Of your allergies
    • Of your current health problems
    • Of your past medical history
    • If you are pregnant or breastfeeding
  • The following may occur during treatment with Mayzent:
    • Infections (increased risk)
    • Progressive multifocal leukoencephalopathy
    • Macular edema
    • Low heart rate and delays in atrioventricular conduction
    • Respiratory issues
    • Liver issues
    • Skin cancer
    • High blood pressure
    • Harm to a fetus. Female patients are advised to use effective contraceptive methods during treatment and for 10 days after Mayzent treatment has been stopped.
  • Patients should not receive live vaccines while they are being treated with Mayzent and for up to 4 weeks after stopping treatment.

Side Effects

Mayzent side effects include but are not limited to headache, high blood pressure, and increased liver enzymes. Contact your healthcare provider right away if you have worrisome or persistent side effects.

Here, you can buy Mayzent!

Reference

Mayzent. East Hanover, NJ: Novartis Pharmaceuticals Corporation; 2023.




IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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