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We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!
Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.
To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.
Terms & Conditions of Program
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Mekinist (trametinib) is a prescription medication used for treating the following conditions:
Mekinist is available as an oral tablet in 0.5 mg and 2 mg strengths. It is also available in a 4.7 mg oral solution.
Fact Table | |
---|---|
Formula | C26H23FIN5O4 |
License | FDA approved |
Bioavailability | 72% |
Legal status | Prescription only |
Chemical Name | N-[3-[3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3-oxo-1H-pyrazol-4-yl]-1H-indazol-6-yl]acetamide |
Elimination half-life | Approximately 4.5 days |
Dosage (Strength) | 0.5 mg, 2 mg tablets |
Pregnancy | Not recommended; consult a healthcare provider |
Brands | Mekinist |
Protein binding | ~97.4% |
PubChem CID | 11707110 |
MedlinePlus | a613041 |
ChEBI | 78543 |
ATC code | L01XE25 |
DrugBank | DB08911 |
KEGG | D09996 |
Routes of administration | Oral |
Take Mekinist exactly as prescribed by your doctor. Carefully read the medication guide that comes with your prescription.
Mekinist dosing:
Your doctor will decide on an appropriate treatment plan and dose for you based on your condition, age, and body weight. The medication is recommended to be taken at least 1 hour before or 2 hours after a meal.
Mekinist storage:
Keep Mekinist tablets in their original container in the refrigerator between 2°C to 8°C (36°F to 46°F). Keep out of light and away from moisture. Do not throw away the desiccant packet that is in the bottle; it helps keep the medication dry.
Keep reconstituted Mekinist oral solution in the original bottle below 25°C (77°F); avoid freezing. Properly dispose of the oral solution after the “discard after” date that is written on the bottle.
Keep the medication out of reach of children.
If you have any questions or concerns regarding your Mekinist prescription, contact your doctor or pharmacist.
The active ingredient in Mekinist is trametinib.
Inactive ingredients in the tablets include colloidal silicon dioxide, croscarmellose sodium, hypromellose, magnesium stearate (vegetable source), mannitol, microcrystalline cellulose, sodium lauryl sulfate, hypromellose, iron oxide red (2 mg tablets), iron oxide yellow (0.5 mg tablets), polyethylene glycol, polysorbate 80 (2 mg tablets), and titanium dioxide.
Inactive ingredients in the oral solution include betadex sulfobutyl ether sodium, citric acid monohydrate, dibasic sodium phosphate, methylparaben, potassium sorbate, sucralose, and strawberry flavor.
There are no contraindications to Mekinist per the most recent Prescribing Information.
Rash, diarrhea, and lymphedema are common Mekinist side effects. However, other side effects may also occur. Immediately contact your doctor if you experience side effects that bother you or won’t go away.
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Mekinist. East Hanover, NJ: Novartis Pharmaceuticals Corporation; 2023.