Also Known as Mesna
Top brand choice
Strength | Pack Size | Qty | |
---|---|---|---|
Strength
400mg
|
|||
Strength
600mg
|
We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!
Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.
To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.
Terms & Conditions of Program
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Mesnex (Mesna) is a synthetic medicine that helps protect the body from some of the side effects of certain chemotherapy drugs. It is especially used to prevent a condition called hemorrhagic cystitis, which is bleeding in the bladder caused by the chemotherapy drug ifosfamide. Mesnex works by attaching to harmful substances that ifosfamide creates in the body, making them less dangerous and helping the body get rid of them more safely. Doctors can give Mesnex either through an injection or as a pill.
Fact Table | |
Formula | C2H5NaO3S2 |
License | US FDA, EMA |
Bioavailability | 45-79% (oral) |
Legal status | Prescription only (Rx) |
Chemical Name | Sodium 2-mercaptoethane sulfonate |
Elimination half-life | 0.36-1.17 hours |
Dosage (Strength) | 400 mg, 600 mg tablets; 100 mg/mL injection |
Pregnancy | Consult a doctor (Category B) |
Brands | Mesnex |
Protein binding | 69-75% |
PubChem CID | 5192 |
MedlinePlus | a695015 |
ChEBI | 50692 |
ATC code | V03AF01 |
DrugBank | DB06782 |
KEGG | D02345 |
Routes of administration | Oral, Intravenous |
Mesna is typically administered intravenously (IV) and should be given under the direct supervision of a healthcare provider. The standard dosage of Mesnex can be given through several IV injections or by giving an IV injection followed by oral tablets. The schedule for taking these doses should be repeated on each day that ifosfamide is given. If the dose of ifosfamide changes, the amount of Mesna may need to be changed accordingly.
The active ingredient in Mesnex is Mesna.
Do not use Mesnex if you have any of the following conditions:
Mesnex is often used alongside the chemotherapy agent ifosfamide, and it can cause various side effects. The most frequent are nausea, vomiting, diarrhea, and constipation, fatigue, fever, loss of appetite, and stomach pain. Other common effects include headaches, hair loss, sleepiness, and changes in blood counts, such as decreased white and red blood cells and platelets, which could lead to increased risk of infections and bleeding.
Mesnex can trigger severe allergic reactions that might occur with your first treatment or after several months. Immediate medical attention is necessary if you notice symptoms like fever, facial swelling, difficulty breathing, severe skin reactions such as rash, hives, redness, blisters, or peeling.