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| Strength | Pack Size | Qty | |
|---|---|---|---|
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Strength
Solution 121g / 4 sachets
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MoviPrep (polyethylene glycol 3350, sodium sulfate, sodium chloride, potassium chloride, sodium ascorbate, and ascorbic acid for oral solution) is a laxative prescribed to adults for cleansing the colon before a colonoscopy.
MoviPrep comes in 2 pouches for reconstituting in water:
| Fact Table | |
|---|---|
| Formula | PEG 3350: (C2H4O)n • H2O Sodium sulfate: Na2SO4 Sodium chloride: NaCl Potassium chloride: KCl Ascorbic acid: C6H8O6 Sodium ascorbate: C6H7NaO6 |
| License | FDA approved |
| Bioavailability | Not systemically absorbed; acts locally in the GI tract |
| Legal status | Prescription only |
| Chemical Name | Polyethylene Glycol 3350, Sodium Sulfate, Sodium Chloride, Potassium Chloride, Ascorbic Acid, Sodium Ascorbate |
| Elimination half-life | Not applicable (excreted in feces) |
| Dosage (Strength) | PEG 3350: 100 g Sodium sulfate: 7.5 g Sodium chloride: 2.691 g Potassium chloride: 1.015 g Ascorbic acid: 4.7 g Sodium ascorbate: 5.9 g (per 2 liters of reconstituted solution) |
| Pregnancy | Generally considered safe; consult a healthcare provider |
| Brands | Moviprep |
| Protein binding | Not applicable |
| PubChem CID | PEG 3350: 29760 Sodium sulfate: 24437 Sodium chloride: 5234 Potassium chloride: 4873 Ascorbic acid: 54670067 Sodium ascorbate: 23667648 |
| MedlinePlus | a608010 |
| ChEBI | PEG 3350: 5325 Sodium sulfate: 32195 Sodium chloride: 26710 Potassium chloride: 48649 Ascorbic acid: 49122 Sodium ascorbate: 32032 |
| ATC code | A06AD10 |
| DrugBank | DB01359 (PEG 3350), DB09193 (Sodium sulfate), DB09153 (Sodium chloride), DB09154 (Potassium chloride), DB00126 (Ascorbic acid), DB01365 (Sodium ascorbate) |
| KEGG | D01249 (PEG 3350), D01255 (Sodium sulfate), D01545 (Sodium chloride), D01550 (Potassium chloride), D00031 (Ascorbic acid), D01369 (Sodium ascorbate) |
| Routes of administration | Oral |
MoviPrep should be used as your doctor has instructed. Read the medication guide that comes with the product for further instructions for use.
For optimal preparation for your colonoscopy, two doses should be completed.
Once you start MoviPrep, refrain from drinking anything besides clear liquids until after your colonoscopy. Refrain from consuming alcohol, milk, or any red, purple, or pulp-containing foods and drinks. Other laxatives should be avoided. Oral medications should not be taken within 1 hour of starting each dose of MoviPrep. Ensure that you finish the second dose at least 2 hours before the colonoscopy.
Once MoviPrep is mixed with water, it should be kept upright in a refrigerator; use within 24 hours.
Any questions or concerns may be referred to your doctor or pharmacist.
Polyethylene glycol (PEG) 3350, sodium sulfate, sodium chloride, and potassium chloride are the active ingredients in Pouch A. Ascorbic acid and sodium ascorbate are the active ingredients in Pouch B.
Aspartame, acesulfame potassium, and lemon flavoring including citral, lemon oil and lime oil, maltodextrin, xanthan gum, and vitamin E are the inactive ingredients in Pouch A.
MoviPrep should not be administered to patients with gastrointestinal obstruction, bowel perforation, gastric retention, ileus, toxic colitis or megacolon, or an allergy to any of its ingredients.
MoviPrep side effects include but are not limited to general discomfort, stomach pain, nausea, vomiting, abdominal distension, anal discomfort, thirst, hunger, rigor, and dizziness. Inform your doctor right away of any bothersome or persistent side effects you experience.
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MoviPrep. Bridgewater, NJ: Salix Pharmaceuticals; 2023.
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