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| Strength | Pack Size | Qty | |
|---|---|---|---|
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Strength
40mg
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We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!
Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.
To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.
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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Nerlynx, also known as neratinib, is a medication used to treat certain types of breast cancer. This drug works as a tyrosine kinase inhibitor, which means it interferes with the action of enzymes that promote cell growth, particularly in cancer cells. It helps block the signals that encourage the cancer to grow, especially in cases where the cancer cells have an excess of a protein called human epidermal growth factor receptor 2 (HER2). It is commonly prescribed to treat HER2-overexpressed or amplified breast cancer and may be used after initial treatments to lower the risk of disease recurrence.
| Fact Table | |
|---|---|
| Formula | C30H29ClN6O3 |
| License | FDA approved |
| Bioavailability | 19-76% |
| Legal status | Prescription only |
| Chemical Name | Neratinib |
| Elimination half-life | 7-17 hours |
| Dosage (Strength) | 40 mg tablets |
| Pregnancy | Contraindicated |
| Brands | Nerlynx |
| Protein binding | >99% |
| PubChem CID | 9915748 |
| MedlinePlus | a617035 |
| ChEBI | 65386 |
| ATC code | L01XE45 |
| DrugBank | DB11828 |
| KEGG | D09694 |
| Routes of administration | By mouth |
Patients should take Nerlynx orally with food to improve absorption. The typical dosage is 240 mg, which usually amounts to six tablets, taken once a day. The treatment duration typically lasts for a year, following the completion of trastuzumab-based therapy in those with early-stage HER2-positive breast cancer. It's vital to follow a healthcare provider's guidance carefully to manage any health issues that arise.
Neratinib is the active ingredient in Nerlynx.
There are no specific contraindications stated on the drug label. However, patients who have demonstrated a severe allergic reaction to any ingredient of Nerlynx should avoid the medication.
Common Nerlynx side effects include diarrhea, nausea, and stomach pain. Additional common issues include fatigue, vomiting, skin rashes, mouth sores, decreased appetite, and muscle spasms. Some may notice changes in nail color, dry skin, abdominal swelling, nosebleeds, weight loss, and urinary tract infections.
One concern with Nerlynx is its potential to cause liver problems. Monitoring involves blood tests before starting treatment and periodically thereafter, especially during the first three months. If you notice symptoms like fatigue, nausea, pain in the upper right abdomen, fever, rash, itching, or yellowing of the skin or eyes, contact your healthcare provider immediately. These signs could indicate serious liver issues, requiring changes to or discontinuation of treatment.
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Canada Drugs Direct employs dedicated, professional licensed pharmacists to ensure that each and every order is reviewed before it is dispensed for the safety and health of our customers. At CanadaDrugsDirect.com, your health is our top priority.
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