Nimotop (Nimodipine)

Prescription medicineOnly Available By Prescription
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30mg
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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Your doctor may prescribe Nimotop if you have experienced a bleed in the brain (subarachnoid hemorrhage). A brain bleed is an emergency, and symptoms can include loss of consciousness, nausea, vomiting, double vision, severe headache, sensitivity to light, and confusion. If you are experiencing these symptoms, call emergency services.

Nimotop is a calcium channel blocker that works by targeting cerebral blood vessels. By attaching to calcium channels in the cerebral vessels, Nimotop prevents the flow of calcium into muscle cells, which relaxes the blood vessels. Relaxation of the blood vessels then reduces the risk of brain damage.

Fact Table
Formula C21H26N2O7
License FDA approved
Bioavailability Approximately 13% (due to first-pass metabolism)
Legal status Prescription only
Chemical Name (±)-4-(3-Benzylpiperidin-1-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid 3-ethyl 5-methyl ester
Elimination half-life Approximately 1-2 hours
Dosage (Strength) 30 mg tablets, 0.2 mg/mL oral solution
Pregnancy Category C; consult a healthcare provider
Brands Nimotop, Nimodip
Protein binding Approximately 95%
PubChem CID 4485
MedlinePlus a685027
ChEBI 7572
ATC code C08CA06
DrugBank DB00393
KEGG D00445
Routes of administration Oral, Intravenous (off-label)

Directions

The standard dosage is 60 mg capsule every four hours over 21 days. If you have a history of liver disease, your doctor will likely adjust the dosage to 30 mg every four hours.

Nimotop should be taken on an empty stomach, one hour before or two hours after meals.

The capsules cannot be crushed, chewed, or opened. Commencement of Nimotop within 96 hours of a subarachnoid hemorrhage is crucial for optimal therapeutic outcomes.

Ingredients

The active ingredient in Nimotop is nimodipine.

Interactions

Common drug-drug interactions may include:

  • Boceprevir
  • Carbamazepine
  • Ceritinib
  • Clarithromycin
  • Clopidogrel
  • Cobicistat
  • Conivaptan
  • Dalfopristin
  • Dantrolene
  • Darunavir
  • Delavirdine
  • Dexamethasone
  • Digoxin
  • Epirubicin
  • Fosphenytoin
  • Indinavir
  • Itraconazole
  • Ketoconazole
  • Lacosamide
  • Lopinavir
  • Melphalan
  • Nefazodone
  • Nelfinavir
  • Phenobarbital
  • Phenytoin
  • Posaconazole
  • Quinupristin
  • Rifampin
  • Rifapentine
  • Ritonavir
  • Saquinavir
  • St John's Wort
  • Tacrolimus
  • Telaprevir
  • Telithromycin
  • Valproic Acid
  • Voriconazole

Cautions

Before starting Nimotop, tell your doctor about any high blood pressure, problems with the heart, or liver issues.

Keep an eye on blood pressure while using Nimotop.

If you have a history of stomach problems, tell your healthcare provider.

If you are pregnant or planning to become pregnant, it’s important to talk to the healthcare team before starting Nimotop.

Side Effects

Some of the common adverse reactions may include:

  • Bradyarrhythmia
  • Headache
  • Hypotension
  • Nausea

References

Nimotop [package insert]. West Haven, CT: Bayer; December 2005.



IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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