Only Available By Prescription
Top brand choice
| Strength | Pack Size | Qty | |
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Strength
2.3mg
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Strength
3mg
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Strength
4mg
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Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.
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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Ninlaro is a prescription medication indicated for the treatment of multiple myeloma, a form of blood cancer affecting plasma cells. This condition involves the abnormal proliferation of plasma cells in the bone marrow, leading to various symptoms and complications. Ninlaro is prescribed in combination with lenalidomide and dexamethasone.
Ninlaro is a proteasome inhibitor that disrupts the growth and survival of myeloma cells. By inhibiting the proteasome, a cellular structure essential for protein breakdown, Ninlaro destroys plasma cells that have become cancerous and are replicating too aggressively.
| Fact Table | |
|---|---|
| Formula | C14H23BCl2N2O |
| License | FDA approved |
| Bioavailability | Approximately 58% |
| Legal status | Prescription only |
| Chemical Name | (1R)-1-[(2S)-2,5-dihydro-2-(2,2,5,5-tetramethyl-1,3,2-dioxaborolan-4-yl)-5-(4,5-dichloropyridin-2-yl)-1H-pyrrol-1-yl]-2,2-dimethylpropan-1-one |
| Elimination half-life | Approximately 9.5 days |
| Dosage (Strength) | 2.3 mg, 3 mg, 4 mg capsules |
| Pregnancy | Not recommended; consult a healthcare provider |
| Brands | Ninlaro |
| Protein binding | 99% |
| PubChem CID | 11622938 |
| MedlinePlus | a615038 |
| ChEBI | 85180 |
| ATC code | L01XX50 |
| DrugBank | DB11659 |
| KEGG | D10598 |
| Routes of administration | Oral |
The usual directions are to take Ninlaro on days 1,8, and 15 of a 28-day chemotherapy cycle.
Take Ninlaro one hour before or two hours after meals.
The active ingredient in Ninlaro is ixazomib.
Common drug-drug interactions may include:
Your doctor should monitor your platelet count and at each dose adjustment while taking this medication.
Tell your doctor if you experience severe gastrointestinal side effects like diarrhea, nausea, vomiting, or constipation.
Tell your doctor if you experience pain, numbness, or tingling in your hands or feet during treatment.
Tell your doctor if you have a history of kidney or liver problems before starting this drug.
Tell your healthcare provider if you experience a rash after starting Ninlaro.
Do not take this drug if you are pregnant or trying to become pregnant.
Common adverse reactions to this drug are:
Ninlaro [package insert]. Lexington, MA: Takeda; May 2022.
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