Nplate (Romiplostim)

Prescription medicineOnly Available By Prescription

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Nplate (romiplostim) is a medication that is given via a subcutaneous injection (underneath the skin) to treat immune thrombocytopenia (ITP) in patients who are 1+ years of age.

Fact Table

Formula

C_1538H_2522N_408O_462S_10

License

US FDA, EMA

Bioavailability

70% (Subcutaneous)

Legal status

Prescription only (Rx)

Chemical Name

Romiplostim

Elimination half-life

3-4 days

Dosage (Strength)

125 mcg, 250 mcg, 500 mcg per vial

Pregnancy

Consult a doctor

Brands

Nplate

Protein binding

N/A (Large glycoprotein)

PubChem CID

16158271

MedlinePlus

a609016

ChEBI

68553

ATC code

B02BX04

DrugBank

DB05332

KEGG

D10208

Routes of administration

Subcutaneous (SC)

Directions

A healthcare provider will administer Nplate to you or your child via a subcutaneous injection. An appropriate treatment regimen, including Nplate dosing, will be determined by the doctor based on weight, platelet response, and other therapies.

Refer any questions or concerns to the treating physician.

Ingredients

Romiplostim is the active ingredient in Nplate.

L-histidine, mannitol, polysorbate 20, sucrose, and hydrochloric acid are the inactive ingredients included.

Contraindications

There are no listed contraindications per the most recent Prescribing Information.

Cautions

  • Before you or your child starts Nplate, consult the doctor about:
    • All the medications you or your child takes, including prescription and nonprescription medications
    • Your or your child’s allergies
    • Your or your child’s existing health conditions
    • Your or your child’s past medical history
    • If you or your child is pregnant or breastfeeding
  • Elevated blast cells and increased risk of progression to acute myelogenous leukemia may occur in some patients who have myelodysplastic syndrome and receive Nplate
  • Elevated platelet counts can occur, which may result in issues with blood clotting. Patients with chronic liver disease who are receiving Nplate have experienced portal vein thrombosis.
  • Nplate can cause decreased platelet counts.

Side Effects

Nplate drug side effects in adults include but are not limited to pain in the joints, dizziness, sleep problems, muscle pain, pain in the extremities, abdominal pain, shoulder pain, indigestion, tingling or numbness, and headache.

Nplate side effects in pediatric patients include but are not limited to contusion, upper respiratory tract infection, and oropharyngeal pain.

Contact your or your child’s doctor right away if you or your child experiences bothersome or persistent side effects.

Talk to your or your child’s doctor about Nplate.

Reference

Nplate. Thousand Oaks, CA: Amgen Inc.; 2022.




IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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