Nyvepria (Pegfilgrastim)

Prescription medicineOnly Available By Prescription

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Nyvepria uses:

Nyvepria (pegfilgrastim-apgf) aids your body’s ability to produce more white blood cells known as neutrophils, which are important for helping your body fight infections.

Nyvepria is administered as an injection underneath the skin. It comes in 6 mg/0.6 mL single-dose prefilled syringes.

Fact Table
Formula C845H1343N223O243S9
License FDA approved
Bioavailability 60-70% (subcutaneous)
Legal status Prescription only
Chemical Name Pegfilgrastim
Elimination half-life 15-80 hours
Dosage (Strength) 6 mg/0.6 mL
Pregnancy Consult a healthcare provider
Brands Nyvepria, Neulasta
Protein binding Not significantly bound to plasma proteins
PubChem CID 15842690
MedlinePlus a602002
ChEBI 66913
ATC code L03AA13
DrugBank DB00019
KEGG D02779
Routes of administration Subcutaneous

Directions

Your doctor will decide on your treatment regimen. You or your caregiver should receive training on the proper preparation, administration, and disposal of Nyvepria.

Nyvepria is injected in the thigh, abdomen, upper outer area of the buttocks, or outer area of the upper arm. Let your doctor or pharmacist know about any questions or concerns you may have.

You may also refer to the medication guide that accompanies your prescription for further instructions for use.

Never share needles or syringes with others.

Storage:

Store Nyvepria in the original container and out of light at temperatures between 2°C and 8°C (36°F and 46°F). You should not freeze or shake the medication. If the medication has frozen, allow the prefilled syringe to thaw in the refrigerator before you use it.

Take Nyvepria out of the refrigerator 30 minutes prior to using it so it can reach room temperature. Appropriately throw Nyvepria away if it has been left at room temperature for more than 15 days.

Ingredients

Pegfilgrastim-apgf is the active ingredient in Nyvepria. Acetate, polysorbate 20, sodium, and sorbitol in water for injection are the inactive ingredients.

Contraindications

Nyvepria should not be given to patients who are allergic to human granulocyte colony-stimulating factors such as pegfilgrastim or filgrastim.

Cautions

  • Before you start using Nyvepria, tell your doctor:
    • About all the prescription and nonprescription medications you take
    • About your allergies
    • About your current health problems
    • About your past medical history
    • If you are pregnant or breastfeeding
  • The following may occur with Nyvepria use:
    • Potentially fatal splenic rupture. Notify your doctor right away if you experience pain in the left upper stomach or left shoulder.
    • Acute respiratory distress syndrome. Seek emergency care right away if you experience shortness of breath, trouble breathing, or rapid breathing.
    • Serious allergic reactions, including anaphylaxis. Seek emergency care right away if you develop a rash, shortness of breath, wheezing, dizziness, swelling of your mouth or eyes, fast heart rate, and sweating.
    • Fatal sickle cell crisis. Notify your doctor right away if you have symptoms such as pain or difficulty breathing.
    • Damage to the portion of the kidneys that filter the blood, or glomerulonephritis. Notify your doctor right away if you experience swelling of your face or ankles, dark urine or blood in your urine, or if you are urinating less than usual.
    • Decreased platelets
    • Myelodysplastic syndrome and acute myeloid leukemia. Monitoring for these conditions should occur in patients with breast and lung cancer who are on Nyvepria treatment, as well as chemotherapy and/or radiotherapy.

Side Effects

Nyvepria side effects include but are not limited to bone pain and pain in the arms and legs. Contact your doctor right away if you have worrisome or persistent side effects.

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Reference

Nyvepria. New York, NY: Pfizer Inc.; 2023.




IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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