Ocrevus (Ocrelizumab)

Prescription medicineOnly Available By Prescription

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Ocrevus (ocrelizumab) is a medication given via intravenous infusion for the treatment of multiple sclerosis.

Fact Table

Formula

C6496H10052N1732O2022S42

License

US FDA, EMA

Bioavailability

Not applicable (IV only)

Legal status

Prescription only (Rx)

Chemical Name

Ocrelizumab

Elimination half-life

26 days (range: 14–42 days)

Dosage (Strength)

300 mg/10 mL (first dose split in two infusions); then 600 mg IV every 6 months

Pregnancy

Avoid use; may cross placenta (IgG1 subclass)

Brands

Ocrevus

Protein binding

High (monoclonal antibody)

PubChem CID

86278376

MedlinePlus

a617007

ChEBI

133754

ATC code

L04AA36

DrugBank

DB11963

KEGG

D10745

Routes of administration

Intravenous (IV)

Directions

Your dosage and treatment duration will be determined by your healthcare provider.

Ocrevus will be administered by your healthcare provider, as well as a steroid and an antihistamine prior Ocrevus administration.

Inform your healthcare provider of any questions or concerns you may have.

Ingredients

The active ingredient in Ocrevus is ocrelizumab. Glacial acetic acid, polysorbate 20, sodium acetate trihydrate, and trehalose dihydrate are the inactive ingredients.

Contraindications

Some patients should not receive Ocrevus, including those who have hepatitis B or have ever had a life-threatening infusion reaction to Ocrevus.

Cautions

  • Before your Ocrevus is administered, inform your healthcare provider of:
    • All the medications you take, including prescription and over-the-counter medications
    • Your allergies
    • Your current health problems
    • Your past medical history
    • Your pregnancy or breastfeeding status
  • The following conditions can be caused by Ocrevus:
    • Infusion reactions
    • Infections
    • Progressive multifocal leukoencephalopathy
    • Immune system issues
    • Increased risk of cancer, including breast cancer
    • Immune-mediated colitis
  • Patients on Ocrevus treatments should not receive live vaccines.

Side Effects

Ocrevus infusion side effects include but are not limited to upper respiratory tract infections, infusion reactions, skin infections, and lower respiratory tract infections. Inform your healthcare provider right away if you develop bothersome or persistent side effects.

Talk to your healthcare provider about Ocrevus.

Reference

Ocrevus. South San Francisco, CA: Genentech, Inc.; 2023.




IMPORTANT NOTE: The information provided above is for general awareness and educational purposes only. It is not intended to diagnose, treat, or replace professional medical or veterinary advice. Always consult your physician, pharmacist, or veterinarian regarding the safety, suitability, and proper use of any medication for yourself or your pet.

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