Only Available By Prescription
Top brand choice
| Strength | Pack Size | Qty | |
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Strength
2mg
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Strength
4mg
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Top Generic choice
| Strength | Pack Size | Qty | |
|---|---|---|---|
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Strength
2mg
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Strength
4mg
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You'll have option to make 4 interest-free payments by credit card once your order is confirmed using
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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Olumiant (baricitinib) is a Janus kinase (JAK) inhibitor used to treat moderate to severe rheumatoid arthritis in adults who received one or more tumor necrosis factor (TNF) blockers that did not respond well or could not be tolerated.
Olumiant is supplied in 1 mg and 2 mg tablets.
| Fact Table | |
| Formula |
C16H17N7O2S |
| License |
EU EMA, US DailyMed |
| Bioavailability |
79% |
| Legal status |
Rx-Only |
| Chemical Name |
Baricitinib |
| Elimination half-life |
12.5 hours |
| Dosage (Strength) |
2mg, 4mg |
| Pregnancy |
Contraindicated |
| Brands |
Olumiant |
| Protein binding |
50% |
| PubChem CID |
44205240 |
| MedlinePlus |
a618033 |
| ChEBI |
95341 |
| ATC code |
L04AA37 |
| DrugBank |
DB11817 |
| KEGG |
D10308 |
| Routes of administration |
By mouth |
The recommended dose is 2 mg by mouth once daily. Olumiant can be taken with or without food.
Patients who have kidney problems or take strong Organic Anion Transporter 3 (OAT) inhibitors such as probenecid may be dosed at 1 mg by mouth once daily.
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WARNING: SERIOUS INFECTIONS, MORTALITY, MALIGNANCY, MAJOR ADVERSE CARDIOVASCULAR EVENTS (MACE), AND THROMBOSIS See full prescribing information for complete boxed warning.
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Tell your doctor if you have an active infection or an infection that won't go away or keeps returning. Tell your doctor if you have tuberculosis or if you have been around someone who has tuberculosis. Olumiant may increase the risk for serious infections and opportunistic infections. Contact your doctor immediately if you experience a cough, fever, diarrhea, stomach pain, shortness of breath, weight loss, blood in your phlegm, fatigue, achy muscles, skin that's painful, red, or warm, sores on your body, burning while urinating, or needing to urinate more often.
The risk of death is increased in patients who are at least 50 years old who have one or more risk factors for cardiovascular disease and take a JAK inhibitor.
Olumiant may increase your risk for certain cancers such as lung cancer, skin cancer, and lymphomas.
Tell your doctor if you smoke. Tell your doctor if you have heart problems or if you've had a stroke or heart attack. The risk for major cardiovascular events is increased in patients who are at least 50 years old who have one or more risk factors for cardiovascular disease and take a JAK inhibitor. Seek immediate emergency care if you feel discomfort in your chest, pain or discomfort in your arm, back, neck, stomach, or jaw, shortness of breath, cold sweats, dizziness, weakness in one part or on one side of your body, slurred speech, or tightness, pressure, pain, or heaviness in your chest, throat, neck, or jaw.
Tell your doctor if you have had blood clots. Thrombosis has been reported with the use of Olumiant. Contact your doctor right away if you have pain, swelling, or tenderness in your leg, sudden chest pain, or shortness of breath.
Tell your doctor if you have stomach or intestinal problems. Stomach or intestinal tears may occur with Olumiant treatment. Contact your doctor right away if you develop a fever and stomach pain that persists, and bowel changes.
Tell your doctor if you have low blood counts. Abnormal blood counts may occur with Olumiant.
Live vaccines should not be given to patients receiving Olumiant.
Talk to your doctor about your allergies. Olumiant may cause hypersensitivity reactions that may be severe.
Let your doctor know if you are pregnant or plan to become pregnant.
Let your doctor know if you are breastfeeding or plan to breastfeed.
Tell your doctor about all the medications that you take, including prescription and over-the-counter medications. Olumiant may interact with certain medications which can cause dangerous effects.
Olumiant can cause side effects. The most common include:
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