Only Available By Prescription
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| Strength | Pack Size | Qty | |
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Strength
3mg/ml vial
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Strength
6mg/ml vial
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Strength
9mg/ml vial
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We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!
Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.
To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.
Terms & Conditions of Program
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Your doctor may prescribe pamidronate disodium to treat various bone disorders, including osteoporosis, high calcium levels during cancer, Paget’s disease, and bone metastases.
This medication is pivotal in restoring normal bone health by attaching to calcium phosphate crystals within the bone. Incorporating into these bone crystals, causes pamidronate to prevent bone recycling, maintaining overall bone health. Additionally, pamidronate inhibits the activity of osteoclasts, the bone cells that become overly active during cancer.
| Fact Table | |
|---|---|
| Formula | C3H9NNa2O7P2 |
| License | FDA approved |
| Bioavailability | Bioavailability is irrelevant as it is administered intravenously |
| Legal status | Prescription only |
| Chemical Name | Disodium (3-amino-1-hydroxypropylidene)bisphosphonate |
| Elimination half-life | Approximately 28 hours |
| Dosage (Strength) | 30 mg, 60 mg, 90 mg vials for injection |
| Pregnancy | Category D; use only if the potential benefit justifies the potential risk |
| Brands | Aredia, Pamidronate Disodium |
| Protein binding | Approximately 54% |
| PubChem CID | 5288889 |
| MedlinePlus | a692029 |
| ChEBI | 7410 |
| ATC code | M05BA03 |
| DrugBank | DB00282 |
| KEGG | D00762 |
| Routes of administration | Intravenous |
Administration of pamidronate disodium should be performed only by a trained healthcare professional through intravenous infusion, usually in an infusion clinic.
The maximum dosage per infusion is 90 mg, and the treatment frequency should not exceed every seven days.
The dosage varies based on the specific condition being treated, and adhering to your doctor’s instructions is crucial.
Your doctor may recommend calcium and vitamin D supplements between infusions.
The active ingredient in pamidronate is pamidronate disodium, and the inactive ingredients include mannitol and phosphoric acid.
There are no significant drug-drug interactions between pamidronate and other medications.
Regular dental check-ups are recommended to assess for jaw osteonecrosis.
People who are pregnant or planning to become pregnant should avoid pamidronate.
Before and during therapy, your doctor will monitor calcium, phosphate, magnesium, and potassium levels.
If you have a history of thyroid problems or kidney disease, caution is advised.
Pamidronate is excreted through the kidneys, potentially accumulating to dangerous levels in individuals with kidney disease.
Common adverse reactions to pamidronate may include:
Pamidronate [package insert]. Bedford, OH: Bedford Laboratories; January 2009.
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If you have any questions at all, or would like to place an order, you are encouraged to contact us by toll-free
phone 1-888-904-8467 or email info@canadadrugsdirect.com.
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