Top brand choice
Strength | Pack Size | Qty | |
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Strength
1.5% solution
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Terms & Conditions of Program
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Pennsaid (diclofenac sodium) topical solution 2% w/w, is a prescription nonsteroidal anti-inflammatory drug (NSAID) that is applied topically to treat knee osteoarthritis.
Pennsaid comes in a topical solution.
Diclofenac sodium is Pennsaid’s generic name.
Fact Table | |
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Formula | C14H11Cl2NO2 (Diclofenac sodium) |
License | FDA approved |
Bioavailability | Approximately 6% (topical application) |
Legal status | Prescription only |
Chemical Name | 2-[(2,6-Dichlorophenyl)amino]benzeneacetic acid sodium salt |
Elimination half-life | Approximately 1-2 hours |
Dosage (Strength) | 1.5% and 2% topical solution |
Pregnancy | Avoid use in the third trimester; consult a healthcare provider |
Brands | Pennsaid |
Protein binding | 99.7% |
PubChem CID | 3033 |
MedlinePlus | a689002 |
ChEBI | 47381 |
ATC code | M02AA15 |
DrugBank | DB00586 |
KEGG | D07802 |
Routes of administration | Topical |
Use Pennsaid as directed by the prescribing doctor, who will determine appropriate dosing for you.
Recommended dosing:
Apply 2 pumps on each painful knee two times a day; apply evenly around the front, back, and sides of the knee(s); ensure the skin is clean and dry before applying. Thoroughly wash your hands after use. Let the area completely dry before covering with clothing or applying sunscreen, insect repellant, cosmetics, or other topical products and medications. Avoid skin-to-skin contact until completely dried. Do not get the medication in your eyes, mouth, or nose.
Store Pennsaid at 25°C (77°F) and out of reach of children.
Refer to the information leaflet that accompanies your Pennsaid prescription for further instructions for use.
Contact your doctor or pharmacist about your questions or concerns.
Diclofenac sodium is the active ingredient in Pennsaid.
Dimethyl sulfoxide USP (DMSO, 45.5% w/w), ethanol, purified water, propylene glycol, and hydroxypropyl cellulose are the inactive ingredients included.
Pennsaid should not be used in patients who meet the following criteria:
Pennsaid side effects include but are not limited to application site reactions.
Call your doctor right away if you have bothersome or persistent side effects.
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Pennsaid. Deerfield, IL: Horizon Medicines LLC; 2022.