Pomalyst (Pomalidomide)

Prescription medicineOnly Available By Prescription

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Pomalyst (Pomalidomide) is a third-generation immunomodulatory drug that can modify or regulate the functioning of the immune system. This medication is used to treat multiple myeloma and AIDS-related Kaposi sarcoma. It is typically taken in combination with another medicine, dexamethasone, to treat adults with multiple myeloma who have previously received at least 2 medicines, including a proteasome inhibitor and lenalidomide.

Fact Table

Formula

C13H11N3O4

License

US FDA, US DailyMed, EU EMA

Bioavailability

73%

Legal status

Rx-Only

Chemical Name

Pomalidomide

Elimination half-life

7.5 hours

Dosage (Strength)

4mg

Pregnancy

it may cause birth defects or death to an unborn baby

Brands

Pomalyst

Protein binding

12–44%

PubChem CID

134780

MedlinePlus

a613030

ChEBI

72690

ATC code

L04AX06

DrugBank

DB08910

KEGG

D08976

Routes of administration

By mouth

Directions

The initial dosage for adults with multiple myeloma is 4 milligrams (mg) once daily. It is typically taken on days 1 to 21 of a 28-day cycle, with this schedule repeated every 28 days. A healthcare provider may adjust this dosage as needed, based on tolerance and effectiveness. When taking Pomalyst, follow the directions on the prescription label carefully. If any part of the directions is unclear, consult a healthcare provider.

Ingredients

Pomalidomide is the active ingredient in Pomalyst. Along with the active ingredient, Pomalyst capsules may contain several inactive ingredients.

Contraindications

Pomalyst should not be used by pregnant women or women who may become pregnant during treatment. It is critical that patients using Pomalyst take appropriate measures to prevent pregnancy during their treatment and for four weeks after stopping the medication. In addition, Pomalyst may not be suitable for patients with a history of severe hypersensitivity reactions to the drug or its components.

Cautions

  • Before starting Pomalyst, inform your healthcare provider of the following:
    • Any health issues, particularly those related to liver or kidney function.
    • If you use tobacco products.
    • If you're expecting or nursing, as Pomalyst carries a high risk of causing serious harm to an unborn baby.
  • Combining Pomalyst with specific drugs for multiple myeloma treatment can significantly increase health risks, so a detailed consultation with your doctor is necessary.
  • Regular blood tests are crucial to monitor neutropenia, a condition of low white blood cells, which can arise during treatment.
  • Patients may experience liver issues, even failure, so monthly liver function tests are recommended to detect any problems early.
  • Discontinue Pomalyst at once if severe skin reactions occur, and seek immediate medical advice.
  • High tumor burden patients should be monitored for tumor lysis syndrome, a serious condition that requires proactive management.
  • Be alert for any immediate allergic reactions like facial swelling or breathing issues, and stop Pomalyst immediately if these occur.

Side Effects

The use of Pomalyst is linked to a risk of side effects. The most common side effects of Pomalyst may include tiredness, muscle weakness, irregular bowel movements, back pain, difficulty breathing, and nausea. There are also severe risks associated with its use, such as the formation of blood clots, which may lead to heart attacks or strokes. In addition, this medication carries potential teratogenic effects in pregnancy. If you notice side effects that are persistent or worsening, promptly consult a medical professional.

References:

  1. Pomalyst (Pomalidomide) Product Monograph. Princeton, NJ: Bristol Myers Squibb; 2023.
  2. Pomalyst (Pomalidomide) Drug Label Information. Princeton, NJ: Bristol Myers Squibb; 2023.



IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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