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Rinvoq ER (Upadacitinib)

Prescription medicineOnly Available By Prescription
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Strength Pack Size Qty
Strength
15mg
Pack Size
Qty
Strength
30mg
Pack Size
Qty
Strength
45mg
Pack Size
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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Rinvoq is a medication prescribed to treat rheumatoid arthritis (RA). Rinvoq is reserved for patients who have tried and failed the medication methotrexate. It can be taken with methotrexate or with other RA medications.

RA is an inflammatory joint condition with symptoms including pain, swelling, redness, and tenderness.

Rinvoq modulates the immune system and makes it less active. Reducing the immune system helps to relieve symptoms of RA. 

Fact Table

Formula

C17H19F3N6O

License

US FDA, EU EMA

Bioavailability

80%

Legal status

Rx-only

Chemical Name

Upadacitinib

Elimination half-life

9–14 hours

Dosage (Strength)

15mg

Pregnancy

Not Recommended

Brands

Rinvoq ER

Protein binding

52%

PubChem CID

58557659

MedlinePlus

a619051

ChEBI

-

ATC code

L04AA44

DrugBank

DB15091

KEGG

D10994

Routes of administration

By mouth

Directions

The usual Rinvoq dosing is 15 mg by mouth once daily.

Take Rinvoq exactly as prescribed by your doctor.

Ingredients

Upadacitinib is the active ingredient in Rinvoq.

Interactions

Rinvoq has many potential drug-drug interactions. Tell your doctor and pharmacist about all of the medications you are taking before starting Rinvoq.

Common drug-drug interactions include:

  • Apalutamide
  • Atazanavir
  • Carbamazepine
  • Ceritinib
  • Clarithromycin
  • Darunavir
  • Enzalutamide
  • Fosphenytoin
  • Idelalisib
  • Indinavir
  • Itraconazole
  • Ketoconazole
  • Lonafarnib
  • Lopinavir
  • Lumacaftor
  • Lumacaftor-ivacaftor
  • Mifepristone
  • Mitotane
  • Nefazodone
  • Nelfinavir
  • Ombitasvir-paritaprevir-ritonavir
  • Phenobarbital
  • Phenytoin
  • Posaconazole
  • Primidone
  • Rifampin (rifampicin)
  • Saquinavir
  • Telithromycin
  • Tucatinib
  • Voriconazole

Cautions

Tell your doctor if you have any latent infections, including tuberculosis or other viral, bacterial, or fungal infections. Rinvoq can re-activate latent infections. 

Rinvoq has been associated with the development of certain types of cancers, including lymphomas.

Medications similar to Rinvoq may increase the risk of blood clots, including deep vein thrombosis, pulmonary embolism, and stroke.

Rinvoq should not be used in combination with potent immunosuppressants like azathioprine and cyclosporine.

Side Effects

Rinvoq is associated with the following side effects:

  • Cough
  • Fever
  • Increased liver enzymes
  • Nausea
  • Pyrexia
  • Upper respiratory tract infection

References

  1. Rinvoq [package insert]. Whippany, NJ: Abbvie; 2019.

IMPORTANT NOTE: The information provided above is for general awareness and educational purposes only. It is not intended to diagnose, treat, or replace professional medical or veterinary advice. Always consult your physician, pharmacist, or veterinarian regarding the safety, suitability, and proper use of any medication for yourself or your pet.

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April 16, 2025 by Elizabeth A. (Washington, United States)
“Easy and streamlined way to order”
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“Always happy with my service and products. Saves me a lot on my prescription.”
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“Fast, well priced”
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