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| Strength | Pack Size | Qty | |
|---|---|---|---|
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Strength
25mg
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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Rydapt (midostaurin) is a prescription medication that is used with other treatments for acute myeloid leukemia (AML) that has been newly diagnosed in adults. It is also prescribed for the treatment of aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematologic neoplasm (SM-AHN), or mast cell leukemia (MCL) in adults.
Rydapt comes in 25 mg capsules for oral administration.
| Fact Table | |
|---|---|
| Formula | C35H30N4O4 |
| License | FDA approved |
| Bioavailability | 57% |
| Legal status | Prescription only |
| Chemical Name | N-benzoyl-staurosporine |
| Elimination half-life | Approximately 20-40 hours |
| Dosage (Strength) | 25 mg capsules |
| Pregnancy | Not recommended; consult a healthcare provider |
| Brands | Rydapt |
| Protein binding | 98% |
| PubChem CID | 9829528 |
| MedlinePlus | a617048 |
| ChEBI | 63708 |
| ATC code | L01XE39 |
| DrugBank | DB06595 |
| KEGG | D08592 |
| Routes of administration | Oral |
Rydapt should be taken as your healthcare provider has instructed. Read the medication guide that accompanies your prescription for product use information.
AML recommended dosing: Take 50 mg by mouth twice daily; take with food.
ASM, SM-AHN, and MCL recommended dosing: Take 100 mg by mouth twice daily; take with food
Rydapt capsules should be stored in their original container at room temperature between 68°F and 77°F (20°C and 25°C) and away from children.
Do not hesitate to reach out to your healthcare provider or pharmacist with any questions or concerns.
Midostaurin is the active ingredient in Rydapt.
Carmine, corn oil mono-di-triglycerides, dehydrated alcohol, ferric oxide red, ferric oxide yellow, gelatin, glycerin 85%, hypromellose 2910, polyethylene glycol 400, polyoxyl 40 hydrogenated castor oil, propylene glycol, purified water, titanium dioxide, and vitamin E are the inactive ingredients.
Rydapt should not be given to patients with an allergy to any of its ingredients.
Rydapt side effects include but are not limited to low white blood cell counts, nausea, sore or inflamed mouth or gut, vomiting, headache, bleeding spots under the skin, musculoskeletal pain, nose bleeds, device-related infection, high blood sugar, abnormal heart rhythms, upper respiratory tract infections, swelling, fatigue, constipation, shortness of breath, and fever. Inform your healthcare provider of any worrisome or persistent side effects you experience.
Looking for a competitive Rydapt 25 mg price? Here, you can buy Rydapt!
Rydapt. East Hanover, NJ: Novartis Pharmaceuticals Corporation; 2023.
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