Senokot S (Sennosides/Docusate Sodium)

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Strength Pack Size Qty
Strength
8.6/50mg
Pack Size
Qty
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Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Senokot-S is medication that combines Sennosides and Docusate Sodium to manage occasional constipation. Sennosides are a type of laxative that works by stimulating the bowel, encouraging it to move and produce a bowel movement. Docusate sodium is a stool softener that makes stools easier to pass. Together, these ingredients usually help people have a bowel movement within 6 to 12 hours after taking the medication. Senokot-S may be helpful for people who are experiencing constipation due to different reasons, such as poor diet, side effects from other medications, or certain health conditions.

Fact Table

Formula

C42H38O20 (Sennosides) + C20H37NaO7S (Docusate Sodium)

License

US FDA (OTC)

Bioavailability

Poor (Sennosides), Minimal systemic absorption (Docusate Sodium)

Legal status

Over-the-counter (OTC)

Chemical Name

Sennosides A & B + Docusate Sodium

Elimination half-life

6-12 hours (Sennosides)

Dosage (Strength)

8.6 mg Sennosides / 50 mg Docusate Sodium per tablet

Pregnancy

Consult a doctor (Category C)

Brands

Senokot-S, Peri-Colace, Dok Plus

Protein binding

Not significant

PubChem CID

73111 (Sennosides), 23673835 (Docusate Sodium)

MedlinePlus

a601113

ChEBI

CHEBI:6778 (Sennosides), CHEBI:31991 (Docusate Sodium)

ATC code

A06AB56

DrugBank

DB09267 (Sennosides), DB11056 (Docusate Sodium)

KEGG

D08351 (Sennosides), D00354 (Docusate Sodium)

Routes of administration

Oral

Directions

Senokot-S tablets are taken orally, typically at bedtime, to support the body's natural processes. The standard Senokot-S dosage for adults and children over the age of 12 is generally 2 tablets once daily, ideally accompanied by a glass of water. For children aged 6 to 12, the recommended dosage is usually 1 tablet once daily. It is advisable to consult a healthcare provider for personalized guidance. If constipation persists after several days of use or if there is a sudden change in bowel habits lasting more than 2 weeks, it is important to seek advice from a healthcare professional.

Ingredients

The active ingredients in Senokot-S are Sennosides and Docusate Sodium.

Contraindications

Avoid taking or using this medication if any of the following apply:

  • You are currently taking mineral oil, unless advised by a doctor
  • You have been using laxative products for more than one week without a doctor's direction

Cautions

  • Before taking Senokot-S, you may want to consult your healthcare provider about the following:
    • Other health conditions you have
    • Any allergies
    • A list of all medications you are currently taking
    • Whether you are pregnant or breastfeeding
  • Senokot-S should not be used for more than one week unless directed by a doctor. Long-term use or overuse can lead to dependence on laxatives and may worsen constipation.
  • If you experience abdominal pain, nausea, vomiting, or a sudden change in bowel habits that lasts more than two weeks, stop using Senokot-S and consult your doctor, as these may be signs of a more serious condition.
  • The senna in Senokot-S may cause urine to turn a yellow or red-brown color. This is harmless and will disappear after discontinuing the medication.
  • Senokot-S may interact with certain medications, such as digoxin, diuretics, and corticosteroids. Your doctor may need to monitor your electrolyte levels or adjust your dosages if you take these medications.
  • If you are scheduled for a colonoscopy or other medical procedure, inform your doctor that you are taking Senokot-S, as it may need to be discontinued before the procedure.

Side Effects

Senokot-S may lead to some mild common side effects that often don't need medical attention. Individuals might experience gas, bloating, and diarrhea. In addition, it's not uncommon for people to have some abdominal discomfort or cramping when taking this medication. If Senokot-S side effects persist or worsen, consult a healthcare provider.

There are serious side effects associated with Senokot-S that may warrant immediate medical care. Signs of an allergic reaction, such as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat need urgent attention. Also, if you notice rectal bleeding, severe stomach pain, nausea, vomiting, or a lack of bowel movement, stop using the medication and contact a doctor promptly. These symptoms could indicate a more severe condition.

References

  1. Senokot-S (Sennosides/Docusate Sodium) Drug Label Information. Copiague, NY: Ajes Pharmaceuticals, LLC; 2014.


IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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