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We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!
Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.
To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.
Terms & Conditions of Program
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Simponi (Golimumab) is a monoclonal antibody that works by blocking a substance in the body called tumor necrosis factor (TNF). It falls under the category of TNF inhibitors, which are a type of disease-modifying antirheumatic drug (DMARD). Physicians prescribe Simponi to help manage the symptoms of autoimmune conditions like rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis, which may include reducing joint pain, swelling, and stiffness. The medication typically comes in the form of an injection that patients can administer themselves under the skin.
| Fact Table | |
| Formula | C6538H10040N1732O2032S32 |
| License | US FDA, EMA |
| Bioavailability | 51% (subcutaneous) |
| Legal status | Prescription only (Rx) |
| Chemical Name | Golimumab |
| Elimination half-life | 12-14 days |
| Dosage (Strength) | 50 mg/0.5 mL; 100 mg/mL (subcutaneous injection) |
| Pregnancy | Consult a doctor (Category B) |
| Brands | Simponi, Simponi Aria |
| Protein binding | Not significant |
| PubChem CID | 11960775 |
| MedlinePlus | a610011 |
| ChEBI | CHEBI:133034 |
| ATC code | L04AB06 |
| DrugBank | DB06410 |
| KEGG | D09300 |
| Routes of administration | Subcutaneous, Intravenous |
Simponi can be injected via an autoinjector or a prefilled syringe. The usual dosage for treating conditions such as rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis is 50 mg once a month. It's important to use the proper injection techniques and follow a healthcare provider’s instructions regarding the timing and dosing schedule. When administering a Simponi injection, rotate the injection sites—such as the thigh, abdomen, or upper arm—to reduce the likelihood of reactions at the site of the injection. Patients should also be mindful not to inject into areas where the skin is tender, bruised, red, or hard.
Simponi contains the active ingredient Golimumab.
No contraindications are listed on the FDA label. However, individuals with a known hypersensitivity to Golimumab or any of its components should avoid taking or using this medication.
As with other medications, Simponi is associated with side effects. The most common Simponi side effects may include upper respiratory infections, reactions at the injection site, and viral infections like flu and oral cold sores.
Significant risks of Simponi include serious infections (including TB), hepatitis B reactivation, heart failure, nervous system problems, symptoms similar to lupus, liver issues, low blood counts, and severe allergic reactions. Watch for symptoms like fever, persistent fatigue, yellowing of the skin or eyes, chest pain, and severe rashes. Prompt medical attention is necessary for serious side effects, and ongoing monitoring by a healthcare provider is recommended.
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We pride ourselves on delivering excellent customer service with as much accessibility as possible.
If you have any questions at all, or would like to place an order, you are encouraged to contact us by toll-free
phone 1-888-904-8467 or email info@canadadrugsdirect.com.
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Canada Drugs Direct employs dedicated, professional licensed pharmacists to ensure that each and every order is reviewed before it is dispensed for the safety and health of our customers. At CanadaDrugsDirect.com, your health is our top priority.
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