Sporanox (Itraconazole)

Also Known as Itraspor

Prescription medicineOnly Available By Prescription
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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Sporanox is an antifungal medication that treats fungal infections affecting the organs, skin, and nails. It belongs to the class of triazole antifungals, which inhibit the synthesis of ergosterol, an essential component of fungal cell membranes, thereby disrupting fungal growth and reproduction.

Fact Table
Formula C35H38Cl2N8O4
License FDA approved
Bioavailability 55% (oral; varies with formulation and food intake)
Legal status Prescription only
Chemical Name 4-[4-[4-[4-[[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-[(1R,2R)-1-methyl-2-(prop-1-en-2-yl)cyclopropyl]-1,2,4-triazole-3-one
Elimination half-life Approximately 21 hours
Dosage (Strength) 100 mg capsules, 10 mg/mL oral solution
Pregnancy Category C; consult a healthcare provider
Brands Sporanox
Protein binding 99.8%
PubChem CID 55283
MedlinePlus a692049
ChEBI 6079
ATC code J02AC02
DrugBank DB01167
KEGG D00337
Routes of administration Oral

Directions

Sporanox is available in different formulations, including capsules, oral solution, and intravenous (IV) infusion. The dosage and duration of treatment depend on the type and severity of the fungal infection. It is essential to follow the prescribing physician's instructions carefully and complete the full course of treatment.

Ingredients

The active ingredient in Sporanox is itraconazole.

Interactions

Common drug-drug interactions with this medication may include:

  • Alfuzosin
  • Alprazolam
  • Astemizole
  • Atazanavir
  • Avanafil
  • Bepridil
  • Bromocriptine
  • Cisapride
  • Colchicine
  • Conivaptan
  • Dihydroergotamine
  • Disopyramide
  • Dofetilide
  • Dronedarone
  • Eletriptan
  • Eliglustat
  • Eplerenone
  • Ergoloid Mesylates
  • Ergonovine
  • Ergotamine
  • Felodipine
  • Fesoterodine
  • Finerenone
  • Flibanserin
  • Fluconazole
  • Gepirone
  • Irinotecan
  • Irinotecan Liposome
  • Isavuconazonium Sulfate
  • Ivabradine
  • Levoketoconazole
  • Levomethadyl
  • Lisuride
  • Lomitapide
  • Lovastatin
  • Lurasidone
  • Maraviroc
  • Mavacamten
  • Mesoridazine
  • Metergoline
  • Methadone
  • Methylergonovine
  • Methysergide
  • Midazolam
  • Naloxegol
  • Nelfinavir
  • Nicergoline
  • Nisoldipine
  • Pacritinib
  • Pimozide
  • Piperaquine
  • Posaconazole
  • Quinidine
  • Ranolazine
  • Silodosin
  • Simvastatin
  • Solifenacin
  • Sparfloxacin
  • Telithromycin
  • Terfenadine
  • Thioridazine
  • Ticagrelor
  • Tolvaptan
  • Triazolam
  • Ubrogepant
  • Venetoclax
  • Voclosporin
  • Ziprasidone

Cautions

Use caution if you have a history of liver dysfunction, heart failure, or a history of ventricular arrhythmias.

Sporanox may also prolong the QT interval on electrocardiograms, increasing the risk of serious cardiac arrhythmias.

Sporanox is not recommended during pregnancy unless the potential benefits outweigh the risks.

Your doctor should closely monitor treatment, including your response to treatment and various lab parameters.

Side Effects

Tell your doctor and pharmacist about any of the following side effects while taking Sporanox:

  • Abdominal pain
  • Diarrhea
  • Dizziness
  • Edema
  • Fatigue
  • Fever
  • Headache
  • Hepatotoxicity
  • Hearing loss
  • Hypertension
  • Nausea
  • Pancreatitis
  • Peripheral nerve disease
  • Pruritus
  • Pulmonary edema
  • Rash
  • Rhinitis
  • Sinusitis
  • Upper respiratory infection
  • Vomiting

References

Sporanox (Itraconazole) [package insert]. Raritan, NJ: PriCara; 2009.



IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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