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| Strength | Pack Size | Qty | |
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Strength
100/6mcg (80/4.5mcg) (120 doses/inhaler)
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Strength
200/6mcg(160/4.5mcg) (60 doses/inhaler)
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Strength
200/6mcg (160/4.5mcg) (120 doses/inhaler)
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Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.
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Terms & Conditions of Program
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Symbicort Turbuhaler is a combination medication containing budesonide and formoterol. It is used as a maintenance treatment for asthma and chronic obstructive pulmonary disease (COPD).
Budesonide is a corticosteroid that reduces lung inflammation, while formoterol is a long-acting beta-agonist (LABA) that relaxes the muscles in the airways, making breathing easier. Together, they provide both anti-inflammatory and bronchodilator effects, improving lung function and reducing the amount of asthma attacks or COPD exacerbations.
Asthma is a reactive airway disease characterized by “attacks” that make breathing difficult. It usually affects younger people. Chronic obstructive pulmonary disease (COPD) is a long-term progressive condition in which the airways narrow, and it usually affects older people.
| Fact Table | |
|---|---|
| Formula | Budesonide: C25H34O6 Formoterol: C19H24N2O4 |
| License | FDA approved |
| Bioavailability | Budesonide: Approximately 39% Formoterol: Approximately 61% |
| Legal status | Prescription only |
| Chemical Name | Budesonide: (RS)-11ß,21-Dihydroxy-16a,17a-(butylidenebis(oxy))-pregna-1,4-diene-3,20-dione Formoterol: N-[2-hydroxy-5-[(1RS)-1-hydroxy-2-[[(2RS)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]formamide |
| Elimination half-life | Budesonide: Approximately 2-3.6 hours Formoterol: Approximately 10 hours |
| Dosage (Strength) | 80/4.5 mcg, 160/4.5 mcg per inhalation |
| Pregnancy | Category C; consult a healthcare provider |
| Brands | Symbicort |
| Protein binding | Budesonide: Approximately 85-90% Formoterol: Approximately 61-64% |
| PubChem CID | Budesonide: 5281004 Formoterol: 3083540 |
| MedlinePlus | Budesonide: a608007 Formoterol: a614018 |
| ChEBI | Budesonide: 3207 Formoterol: 31441 |
| ATC code | R03AK07 |
| DrugBank | Budesonide: DB01222 Formoterol: DB00983 |
| KEGG | Budesonide: D07559 Formoterol: D07995 |
| Routes of administration | Inhalation |
The normal directions are to inhale two puffs by mouth twice daily. The total daily dosage will depend on the strength of the medications in the inhaler device.
The active ingredients in Symbicort Turbohaler are budesonide and formoterol.
Common drug-drug interactions with this medication may include:
Tell your doctor if you have a history of cardiovascular disease, hypertension, diabetes, or seizures should use Symbicort Turbuhaler with caution. It may also increase the risk of asthma-related death or hospitalization in some patients, particularly those with poorly controlled asthma.
Regular lung function and symptom monitoring are recommended during treatment with Symbicort Turbuhaler.
Long-term use by pediatric patients can have impacts on growth and development.
Symbicort can increase the risk of infection in the lungs and mouth. Rinse the mouth with water and spit after each usage.
Common side effects with Symbicort Turbohaler may include:
Symbicort [package insert]. Wilmington, DE: AstraZeneca; 2009.
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