Top brand choice
Strength | Pack Size | Qty | |
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Strength
40mg
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Strength
80mg
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Terms & Conditions of Program
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Tagrisso (osimertinib) is a prescription medication for treating adults who have non-small cell lung cancer (NSCLC) with certain abnormal epidermal growth factor receptor (EGFR) genes.
Tagrisso comes in 40 mg and 80 mg tablets for oral administration.
Fact Table | |
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Formula | C28H33N7O2 |
License | FDA approved |
Bioavailability | Approximately 70% |
Legal status | Prescription only |
Chemical Name | N-[2-[2-(dimethylamino)ethyl-methylamino]-4-methoxy-5-[(4-methylpiperazin-1-yl)methyl]phenyl]-4-(1-methylindol-3-yl)pyrimidine-5-carboxamide |
Elimination half-life | Approximately 48 hours |
Dosage (Strength) | 40 mg, 80 mg tablets |
Pregnancy | Not recommended; consult a healthcare provider |
Brands | Tagrisso |
Protein binding | 95% |
PubChem CID | 71496458 |
MedlinePlus | a616032 |
ChEBI | 90938 |
ATC code | L01XE35 |
DrugBank | DB09330 |
KEGG | D10516 |
Routes of administration | Oral |
Tagrisso should be taken as your doctor has directed.
Recommended dose: Take 80 mg by mouth once daily with or without food.
Read the medication guide that comes with your prescription for additional instructions for use.
Store Tagrisso away from children and at 25°C (77°F).
Any questions or concerns may be referred to your doctor or pharmacist.
Osimertinib is the active ingredient in Tagrisso.
Mannitol, microcrystalline cellulose, low-substituted hydroxypropyl cellulose, sodium stearyl fumarate, polyvinyl alcohol, titanium dioxide, macrogol 3350, talc, ferric oxide yellow, ferric oxide red, and ferric oxide black are the inactive ingredients included.
According to the most recent Prescribing Information, there are no contraindications to Tagrisso. Talk to your doctor about whether Tagrisso is right for you.
Tagrisso side effects include but are not limited to blood cell counts that are not within normal range, rash, anemia, diarrhea, musculoskeletal pain, nail toxicity, fatigue, mouth swelling/sores, and dry skin. Notify your doctor right away if you experience bothersome or persistent side effects.
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Tagrisso. Wilmington, DE: AstraZeneca Pharmaceuticals LP; 2024.