Treanda (Bendamustine)

Prescription medicineOnly Available By Prescription
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25mg
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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Your doctor may prescribe Treanda, which is a chemotherapy medication primarily used to treat specific types of cancer, including chronic lymphocytic leukemia (CLL) and non-Hodgkin lymphoma (NHL).

Treanda is an alkylating agent that disrupts the DNA in cancer cells, preventing their growth and leading to cell death. This action helps slow disease progression and can reduce tumor size.

Fact Table
Formula C16H21Cl2N3O2
License FDA approved
Bioavailability Not applicable (intravenous administration)
Legal status Prescription only
Chemical Name 4-[5-(bis(2-chloroethyl)amino)-1-methyl-1H-benzimidazol-2-yl]butanoic acid
Elimination half-life Approximately 30 minutes
Dosage (Strength) 25 mg/m², 120 mg/m² (dosage varies based on the treatment regimen)
Pregnancy Not recommended; consult a healthcare provider
Brands Treanda, Bendeka
Protein binding Approximately 95-96%
PubChem CID 65628
MedlinePlus a607048
ChEBI 31276
ATC code L01AA09
DrugBank DB06770
KEGG D01002
Routes of administration Intravenous

Directions

Treanda is given as an intravenous injection under the supervision of a healthcare professional. It is usually given in an infusion suite or clinic.

The dosage will be determined on an individual basis.

Ingredients

The active ingredient in Treanda is bendamustine.

Interactions

The most common drug-drug interactions may include:

  • Adenovirus Vaccine, Live
  • Amiodarone
  • Bacillus of Calmette and Guerin Vaccine, Live
  • Carbamazepine
  • Cholera Vaccine, Live
  • Ciprofloxacin
  • Dengue Tetravalent Vaccine, Live
  • Ebola Zaire Vaccine, Live
  • Enoxacin
  • Fluvoxamine
  • Fosphenytoin
  • Influenza Virus Vaccine, Live
  • Interferon Alfa-2b
  • Measles Virus Vaccine, Live
  • Mexiletine
  • Mumps Virus Vaccine, Live
  • Obeticholic Acid
  • Peginterferon Alfa-2a
  • Phenytoin
  • Poliovirus Vaccine, Live
  • Rifampin
  • Rotavirus Vaccine, Live
  • Rubella Virus Vaccine, Live
  • Smallpox Monkeypox Vaccine, Live Non-Replicating
  • Smallpox Vaccine
  • Typhoid Vaccine, Live
  • Varicella Virus Vaccine, Live
  • Vemurafenib
  • Yellow Fever Vaccine
  • Zoster Vaccine, Live

Cautions

Tell your doctor if you are pregnant or planning to become pregnant.

Your doctor will monitor blood labs closely during treatment.

Patients should be monitored for fever and other signs of infection.

Treanda should be discontinued if severe skin reactions occur.

Side Effects

Common side effects of this drug are:

  • Acute myeloid leukemia
  • Acute renal failure
  • ALT/SGPT level raised
  • Anaphylaxis
  • Aspartate aminotransferase serum level above reference range
  • Cough
  • Constipation
  • Decreased hemoglobin
  • Decreased neutrophil count
  • Decreased platelet count
  • Dermatologic toxicity
  • Diarrhea
  • Dyspnea
  • Fatigue
  • Febrile neutropenia
  • Fever
  • Headache
  • Hepatitis
  • Hepatotoxicity
  • Hypertensive crisis
  • Hypersensitivity reaction
  • Infusion reaction
  • Infectious disease
  • Injection site extravasation
  • Leukopenia
  • Loss of appetite
  • Lymphocytopenia
  • Myelodysplastic syndrome
  • Myeloproliferative disorder
  • Myelosuppression
  • Nausea
  • Pneumonia
  • Pulmonary fibrosis
  • Rash
  • Sepsis
  • Septic shock
  • Skin cancer, Non-melanoma
  • Squamous cell carcinoma of the bronchus
  • Stevens-Johnson syndrome
  • Stomatitis
  • Thrombocytopenia
  • Toxic epidermal necrolysis
  • Tumor lysis syndrome
  • Vomiting
  • Weight decreased

References

Treanda [package insert]. Frazer, PA: Cephalon; October 2008.



IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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