April 18, 2025 by Mary F. (NH, United States)
“Thank goodness for Canada Drugs Direct! I'm able to save money on my prescription for Mounjaro. It's still not inexpensive but it's a much better price than in the USA.”
Only Available By Prescription
Top brand choice
| Strength | Pack Size | Qty | |
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0.01%/4%/0.05% 15g
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We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!
Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.
To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.
Terms & Conditions of Program
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Tri-Luma Cream uses: Tri-Luma (fluocinolone acetonide, hydroquinone, and tretinoin) cream, 0.01%/4%/0.05% is a medication that is applied topically to the skin to treat melasma, or brown patches on the face.
| Fact Table | |
| Formula | C24H30F2O6 (Fluocinolone), C6H6O2 (Hydroquinone), C20H28O2 (Tretinoin) |
| License | US FDA (Approved in 2002) |
| Bioavailability | Minimal systemic absorption (topical use) |
| Legal status | Rx-only (prescription only) |
| Chemical Name | Fluocinolone acetonide / Hydroquinone / Tretinoin |
| Elimination half-life | Fluocinolone: ~1.3 hours; Tretinoin: ~0.5–2 hours (topical kinetics vary); Hydroquinone: variable |
| Dosage (Strength) | Fluocinolone 0.01%, Hydroquinone 4%, Tretinoin 0.05% (per gram of cream) |
| Pregnancy | Not recommended; Category C – consult a healthcare provider |
| Brands | Tri-Luma |
| Protein binding | Tretinoin: ~95%; Fluocinolone: high; Hydroquinone: unknown |
| PubChem CID | Fluocinolone: 443858; Hydroquinone: 785; Tretinoin: 444795 |
| MedlinePlus | a601124 (Tretinoin), a682060 (Hydroquinone), a682393 (Fluocinolone) |
| ChEBI | Fluocinolone: 31441; Hydroquinone: 17594; Tretinoin: 15367 |
| ATC code | D11AX (various) |
| DrugBank | DB00591 (Fluocinolone), DB09526 (Hydroquinone), DB00755 (Tretinoin) |
| KEGG | D00365 (Fluocinolone), D00554 (Tretinoin), D08078 (Hydroquinone) |
| Routes of administration | Topical |
Tri-Luma Cream should be used as instructed by your doctor. Any questions or concerns about the medication may be referred to your doctor or pharmacist.
Recommended dosing: Apply a thin layer to the affected area(s) once daily, 30 minutes or more before bedtime. After using the cream, wash your hands thoroughly.
Do not go out in the sun, and be sure to wear sunscreen of an SPF of 30 or greater and protective clothing during the day to protect your skin.
Fluocinolone acetonide (a corticosteroid), hydroquinone (a melanin synthesis inhibitor), and tretinoin (a retinoid) are the active ingredients in Tri-Luma Cream.
Butylated hydroxytoluene, cetyl alcohol, citric acid anhydrous, glycerin, glyceryl stearate, magnesium aluminum silicate, methyl gluceth-10, methylparaben, PEG-100 stearate, propylparaben, purified water, sodium metabisulfite, stearic acid, and stearyl alcohol are the inactive ingredients.
Avoid using Tri-Luma Cream if you have an allergy to any of its ingredients.
Common side effects of Tri-Luma Cream include skin redness, burning, peeling, dryness, and itching. These are not all the side effects that can occur. Immediately inform your doctor of any side effects that bother you or won't go away.
Searching for a low Tri-Luma Cream price? You can buy Tri-Luma Cream today at a competitive price!
Product Reviews
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If you have any questions at all, or would like to place an order, you are encouraged to contact us by toll-free
phone 1-888-904-8467 or email info@canadadrugsdirect.com.
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Canada Drugs Direct employs dedicated, professional licensed pharmacists to ensure that each and every order is reviewed before it is dispensed for the safety and health of our customers. At CanadaDrugsDirect.com, your health is our top priority.
